Rapid urine antigen testing for Streptococcus pneumoniae in adults with community-acquired pneumonia: clinical use and barriers

Aaron M Harris; Susan E Beekmann; Philip M Polgreen; Matthew R Moore

doi:10.1016/j.diagmicrobio.2014.05.008

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Rapid urine antigen testing for Streptococcus pneumoniae in adults with community-acquired pneumonia: clinical use and barriers

Journal article

Open access

Peer reviewed

Rapid urine antigen testing for Streptococcus pneumoniae in adults with community-acquired pneumonia: clinical use and barriers

Aaron M Harris, Susan E Beekmann, Philip M Polgreen and Matthew R Moore

Diagnostic microbiology and infectious disease, Vol.79(4), pp.454-457

08/2014

DOI: 10.1016/j.diagmicrobio.2014.05.008

PMCID: PMC5800492

PMID: 24938760

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Abstract

Streptococcus pneumoniae (pneumococcus) is the most common bacterial etiology of community-acquired pneumonia (CAP) in adults, a leading cause of death. The majority of pneumococcal CAP is diagnosed by blood culture, which likely underestimates the burden of disease. The 2007 CAP guidelines recommend routine use of the rapid pneumococcal urinary antigen (UAg) test. To assess the how pneumococcal UAg testing is being used among hospitalized adult CAP patients and what barriers restrict its use, a Web-based survey was distributed in 2013 to 1287 infectious disease physician members of the Emerging Infectious disease Network of the Infectious Disease Society of America. Of 493 eligible responses, 65% use the pneumococcal UAg test. The primary barrier to UAg use was availability (46%). UAg users reported ordering fewer other diagnostic tests and tailoring antibiotic therapy. Increased access to UAg tests could improve pneumonia management and pneumococcal CAP surveillance.

Antigens, Bacterial - immunology

Antigens, Bacterial - urine

Community-Acquired Infections

Disease Management

Health Care Surveys

Humans

Immunologic Tests

Pneumonia, Pneumococcal - diagnosis

Pneumonia, Pneumococcal - epidemiology

Pneumonia, Pneumococcal - immunology

Pneumonia, Pneumococcal - urine

Practice Patterns, Physicians

Streptococcus pneumoniae - immunology

United States - epidemiology

Urinalysis - methods

Details

Title: Subtitle: Rapid urine antigen testing for Streptococcus pneumoniae in adults with community-acquired pneumonia: clinical use and barriers
Creators: Aaron M Harris - Centers for Disease Control and Prevention
Susan E Beekmann - University of Iowa
Philip M Polgreen - University of Iowa
Matthew R Moore - Epidemic Intelligence Service
Resource Type: Journal article
Publication Details: Diagnostic microbiology and infectious disease, Vol.79(4), pp.454-457
DOI: 10.1016/j.diagmicrobio.2014.05.008
PMID: 24938760
PMCID: PMC5800492
NLM abbreviation: Diagn Microbiol Infect Dis
ISSN: 0732-8893
eISSN: 1879-0070
Grant note: CC999999 / Intramural CDC HHS 5U50CK000187 / NCEZID CDC HHS
Language: English
Date published: 08/2014
Academic Unit: Infectious Diseases; Epidemiology; Injury Prevention Research Center; Internal Medicine
Record Identifier: 9984359902902771

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