Journal article
Rapidly Cycling Affective Disorder: Demographics, Diagnosis, Family History, and Course
Archives of general psychiatry, Vol.49(2), pp.126-131
02/01/1992
DOI: 10.1001/archpsyc.1992.01820020046006
PMID: 1550465
Abstract
• Of 919 patients with major affective disorders who completed at least 1 year of a 5-year, semiannual followup, 45 developed a rapidly cycling bipolar course during the first year, but only one developed a rapidly cycling unipolar course. In comparison with patients who showed a non—rapidly cycling bipolar course, those who became rapid cyclers were more likely to be female and to have exhibited depression, hypomania, or cycling between depression and hypomania within the index episode. Family study data revealed no evidence that high cycle frequencies breed true. Rapid cycling was associated with a significantly lower likelihood of recovery in the second year of follow-up but not in the third, fourth, or fifth. These data suggest that rapid cycling is, in the large majority of cases, a transient, nonfamilial manifestation of bipolar affective disorder.
Details
- Title: Subtitle
- Rapidly Cycling Affective Disorder: Demographics, Diagnosis, Family History, and Course
- Creators
- William CoryellJean EndicottMartin Keller
- Resource Type
- Journal article
- Publication Details
- Archives of general psychiatry, Vol.49(2), pp.126-131
- DOI
- 10.1001/archpsyc.1992.01820020046006
- PMID
- 1550465
- NLM abbreviation
- Arch Gen Psychiatry
- ISSN
- 0003-990X
- eISSN
- 1538-3636
- Publisher
- American Medical Association
- Language
- English
- Date published
- 02/01/1992
- Academic Unit
- Psychiatry
- Record Identifier
- 9984003995502771
Metrics
26 Record Views