Journal article
Rate of visual field loss and long-term visual outcome in primary open-angle glaucoma
American journal of ophthalmology, Vol.132(1), pp.47-56
07/2001
DOI: 10.1016/S0002-9394(01)00912-6
PMID: 11438053
Abstract
To evaluate long-term visual field outcome in primary open-angle glaucoma. In this retrospective cohort study, 40 eyes of 40 patients with primary open-angle glaucoma with elevated intraocular pressure and a minimum of 8-year longitudinal series of visual fields were plotted with Goldmann perimeter. Eyes with any other ocular disease except cataract were excluded. Manual grid templates were used to quantify the visual fields. Linear regression was performed to estimate the rate of visual field decline. Pertinent clinical factors were evaluated for statistical association with the rate of decline. Long-term clinical outcome including visual acuity, rate of legal blindness, and rate of medical and surgical interventions was also measured. In the 40 eyes studied, with a mean follow-up of 14 years, the visual field score decreased at the rate of -1.5% per year. Overall, 68% showed significant decrease, and the rate of decrease among these eyes was -2.1% per year. Five eyes became legally blind from glaucoma; the cumulative rate of blindness from glaucoma was 19% at 22 years. Higher intraocular pressure and greater number of antiglaucoma medications on initial presentation were associated with faster and slower deterioration of visual field (compared with the average), respectively. With standard glaucoma therapy, the rate of visual field loss in primary open-angle glaucoma is slow. Lower intraocular pressure and more antiglaucoma medications are associated with slower visual field decline. Legal blindness from glaucoma is 19% over a follow-up of 22 years.
Details
- Title: Subtitle
- Rate of visual field loss and long-term visual outcome in primary open-angle glaucoma
- Creators
- Y H Kwon - Department of Ophthalmology and Visual Sciences, University of Iowa, Iowa City 52242, USA. young-kwon@uiowa.eduChang-sik Kim - University of IowaM B ZimmermanW L AlwardS S Hayreh
- Resource Type
- Journal article
- Publication Details
- American journal of ophthalmology, Vol.132(1), pp.47-56
- Publisher
- United States
- DOI
- 10.1016/S0002-9394(01)00912-6
- PMID
- 11438053
- ISSN
- 0002-9394
- eISSN
- 1879-1891
- Grant note
- EY-3330 / NEI NIH HHS EY-1151 / NEI NIH HHS
- Language
- English
- Date published
- 07/2001
- Academic Unit
- Biostatistics; Ophthalmology and Visual Sciences
- Record Identifier
- 9983980081102771
Metrics
15 Record Views