Journal article
Rating Scales for Cognition in Huntington's Disease: Critique and Recommendations
Movement disorders, Vol.33(2), pp.187-195
02/01/2018
DOI: 10.1002/mds.27227
PMCID: PMC10080408
PMID: 29278291
Abstract
Cognitive impairment is one of the main features of Huntington's disease and is present across the disease spectrum. As part of the International Parkinson's Disease and Movement Disorder Society-sponsored project to review all clinical rating scales used in Huntington's disease, a systematic review of the literature was performed to identify cognitive scales used in Huntington's disease and make recommendations for their use. A total of 17 cognitive scales were identified and evaluated. None of the scales met criteria for a recommended status. For assessing severity of cognitive dysfunction, the Montreal Cognitive Assessment was recommended with caveats. The UHDRS Cognitive Assessment, the UHDRS-For Advanced Patients cognitive section, the Alzheimer's Disease Assessment Scale-Cognitive Subscale, the Frontal Assessment Battery, the Mattis Dementia Rating Scale, the Mini-Mental State Examination, and the Repeatable Battery for the Assessment of Neuropsychological Status were suggested for evaluating severity of cognitive impairment. The MoCA was suggested as a screening tool for cognitive impairment. The major challenge in the assessment of cognition in Huntington's disease is the lack of a formal definition of dementia and/or mild cognitive impairment in this disease. The committee concluded that there is a need to further validate currently available cognitive scales in Huntington's disease, but that it is premature to recommend the development of new scales. Recently developed Huntington's disease-specific scales, such as the Huntington's Disease-Cognitive Assessment Battery, hold promise but require the completion of more comprehensive clinimetric development. (c) 2017 International Parkinson and Movement Disorder Society
Details
- Title: Subtitle
- Rating Scales for Cognition in Huntington's Disease: Critique and Recommendations
- Creators
- Tiago A. Mestre - University of OttawaAnne-Catherine Bachoud-Levi - École Normale Supérieure - PSLJohan Marinus - Leiden University Medical CenterJulie C. Stout - Monash UniversityJane S. Paulsen - University of IowaPeter Como - Center for Devices and Radiological HealthKevin Duff - University of UtahCristina Sampaio - CHDI FoundationChristopher G. Goetz - Rush University Medical CenterEsther Cubo - Hospital General YagüeGlenn T. Stebbins - Rush University Medical CenterPablo Martinez-Martin - Instituto de Salud Carlos IIIMembers of the MDS Committee on Rating Scales Development
- Resource Type
- Journal article
- Publication Details
- Movement disorders, Vol.33(2), pp.187-195
- DOI
- 10.1002/mds.27227
- PMID
- 29278291
- PMCID
- PMC10080408
- NLM abbreviation
- Mov Disord
- ISSN
- 0885-3185
- eISSN
- 1531-8257
- Publisher
- Wiley
- Number of pages
- 9
- Grant note
- R01 HG003330 / NHGRI NIH HHS; United States Department of Health & Human Services; National Institutes of Health (NIH) - USA; NIH National Human Genome Research Institute (NHGRI) R01NS105509 / NATIONAL INSTITUTE OF NEUROLOGICAL DISORDERS AND STROKE; United States Department of Health & Human Services; National Institutes of Health (NIH) - USA; NIH National Institute of Neurological Disorders & Stroke (NINDS) R01 NS040068; R01 NS054893 / NINDS NIH HHS; United States Department of Health & Human Services; National Institutes of Health (NIH) - USA; NIH National Institute of Neurological Disorders & Stroke (NINDS)
- Language
- English
- Date published
- 02/01/2018
- Academic Unit
- Psychiatry; Psychological and Brain Sciences
- Record Identifier
- 9984383279702771
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