Recent Advances in Computed Tomography Imaging in Chronic Obstructive Pulmonary Disease

Sandeep Bodduluri; Joseph M Reinhardt; Eric A Hoffman; John D Newell Jr; Surya P Bhatt

doi:10.1513/AnnalsATS.201705-377FR

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Recent Advances in Computed Tomography Imaging in Chronic Obstructive Pulmonary Disease

Journal article

Open access

Peer reviewed

Recent Advances in Computed Tomography Imaging in Chronic Obstructive Pulmonary Disease

Sandeep Bodduluri, Joseph M Reinhardt, Eric A Hoffman, John D Newell Jr and Surya P Bhatt

Annals of the American Thoracic Society, Vol.15(3), pp.281-289

03/2018

DOI: 10.1513/AnnalsATS.201705-377FR

PMCID: PMC5880521

PMID: 28812906

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Abstract

Lung imaging is increasingly being used to diagnose, quantify, and phenotype chronic obstructive pulmonary disease (COPD). Although spirometry is the gold standard for the diagnosis of COPD and for severity staging, the role of computed tomography (CT) imaging has expanded in both clinical practice and research. COPD is a heterogeneous disease with considerable variability in clinical features, radiographic disease, progression, and outcomes. Recent studies have examined the utility of CT imaging in enhancing diagnostic certainty, improving phenotyping, predicting disease progression and prognostication, selecting patients for intervention, and also in furthering our understanding of the complex pathophysiology of this disease. Multiple CT metrics show promise for use as imaging biomarkers in COPD.

Disease Progression

Humans

Lung - diagnostic imaging

Lung - physiopathology

Pulmonary Disease, Chronic Obstructive - diagnostic imaging

Pulmonary Disease, Chronic Obstructive - physiopathology

Spirometry

Tomography, X-Ray Computed

Details

Title: Subtitle: Recent Advances in Computed Tomography Imaging in Chronic Obstructive Pulmonary Disease
Creators: Sandeep Bodduluri - University of Alabama at Birmingham
Joseph M Reinhardt - University of Iowa
Eric A Hoffman - University of Iowa
John D Newell Jr - University of Iowa
Surya P Bhatt - University of Alabama at Birmingham
Resource Type: Journal article
Publication Details: Annals of the American Thoracic Society, Vol.15(3), pp.281-289
DOI: 10.1513/AnnalsATS.201705-377FR
PMID: 28812906
PMCID: PMC5880521
NLM abbreviation: Ann Am Thorac Soc
ISSN: 2325-6621
eISSN: 2325-6621
Publisher: American Thoracic Society
Grant note: P30 ES005605 / NIEHS NIH HHS K23 HL133438 / NHLBI NIH HHS R01 HL130883 / NHLBI NIH HHS P30 DK054759 / NIDDK NIH HHS
Language: English
Date published: 03/2018
Academic Unit: Roy J. Carver Department of Biomedical Engineering; Radiology; Internal Medicine
Record Identifier: 9984196992702771

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