Recent advancements in management for noncolorectal, nonneuroendocrine hepatic metastases

Hassan Aziz; Ye In Christopher Kwon; Andrew Min-Gi Park; Alan Lai; Kerry Yi Chen Lee; Dean Zhang; Yeseo Kwon; Timothy M. Pawlik

doi:10.1016/j.gassur.2024.08.012

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Recent advancements in management for noncolorectal, nonneuroendocrine hepatic metastases

Journal article

Peer reviewed

Recent advancements in management for noncolorectal, nonneuroendocrine hepatic metastases

Hassan Aziz, Ye In Christopher Kwon, Andrew Min-Gi Park, Alan Lai, Kerry Yi Chen Lee, Dean Zhang, Yeseo Kwon and Timothy M. Pawlik

Journal of gastrointestinal surgery, Vol.28(11), pp.1922-1932

11/2024

DOI: 10.1016/j.gassur.2024.08.012

PMID: 39154708

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Abstract

Owing to the heterogeneity of underlying primary tumors, noncolorectal, nonneuroendocrine metastases to the liver (NCNNMLs), although relatively rare, pose major challenges to treatment and long-term management. Despite being considered the gold standard for colorectal cancer liver metastases, the role of surgical resection for NCNNML remains controversial. Furthermore, advancements in locoregional treatment modalities, such as ablation and various chemotherapeutic modalities, have contributed to the treatment of patients with NCNNML. This was a comprehensive review of literature that used Medline/PubMed, Google Scholar, the Cochrane Library, and the Web of Science, which were accessed between 2014 and 2024. NCNNMLs are rare tumor entities with varied presentation and outcomes. A multidisciplinary approach, which includes chemotherapy, surgery, and interventional radiologic techniques, can be implemented with good results. Given the complex nature of NCNNML, its management should be highly individualized and multidisciplinary. Locoregional treatments, such as surgical resection and/or ablation, may be more appropriate for select patients and should be offered as a viable therapeutic option for a subset of individuals.

Gastric cancer

Hepatic metastases

Liver resection

Liver transplant

Melanoma

Details

Title: Subtitle: Recent advancements in management for noncolorectal, nonneuroendocrine hepatic metastases
Creators: Hassan Aziz - University of Iowa
Ye In Christopher Kwon - Virginia Commonwealth University
Andrew Min-Gi Park - Virginia Commonwealth University
Alan Lai - Virginia Commonwealth University
Kerry Yi Chen Lee - Virginia Commonwealth University
Dean Zhang - Virginia Commonwealth University
Yeseo Kwon - Tufts University
Timothy M. Pawlik - The Ohio State University Wexner Medical Center
Resource Type: Journal article
Publication Details: Journal of gastrointestinal surgery, Vol.28(11), pp.1922-1932
Publisher: Elsevier Inc
DOI: 10.1016/j.gassur.2024.08.012
PMID: 39154708
ISSN: 1091-255X
eISSN: 1873-4626
Language: English
Electronic publication date: 08/16/2024
Date published: 11/2024
Academic Unit: Surgery
Record Identifier: 9984701745502771

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