Journal article
Recent weight gain in patients with newly diagnosed obstructive sleep apnea
Journal of hypertension, Vol.17(9), pp.1297-1300
09/1999
DOI: 10.1097/00004872-199917090-00009
PMID: 10489107
Abstract
OBJECTIVEPatients with obstructive sleep apnea are often obese. Obesity may contribute to both sleep apnea itself and to the cardiovascular risk associated with sleep apnea. Weight loss in obese patients with sleep apnea may alleviate symptoms and decrease the severity of sleep apnea. Whether patients with obstructive sleep apnea are indeed predisposed to recent weight gain, as compared with similarly obese subjects without sleep apnea, is not known.
PATIENTS AND METHODSWe compared 1-year weight histories in 53 male and female patients newly diagnosed with obstructive sleep apnea, compared with 24 controls matched for gender, age, body mass index, and percent body fat. Sleep apnea patients had never been treated. Control subjects were proven to be free of sleep-disordered breathing by overnight polysomnography.
RESULTSPatients with obstructive sleep apnea (n = 53) had a significant recent weight gain of 7.4 ± 1.5 kg compared with a weight loss of 0.5 ± 1.7 kg (P = 0.001) in similarly obese controls (n = 24). Male patients with obstructive sleep apnea (n = 28) had a history of significant weight gain (6.8 ± 2.3 kg) over the year preceding the study compared with male control subjects (n = 13), in whom average weight fell by 0.58 ± 2.4 kg (P = 0.03). Female patients (n = 25) with obstructive sleep apnea had an 8.0 ± 1.9 kg weight gain compared with female controls (n = 11) who had a history of weight loss of 0.46 ± 2.6 kg (P = 0.02).
CONCLUSIONThese findings support the concept that patients with obstructive sleep apnea may be susceptible to increasing obesity in the period preceding the diagnosis of obstructive sleep apnea.
Details
- Title: Subtitle
- Recent weight gain in patients with newly diagnosed obstructive sleep apnea
- Creators
- Bradley Phillips - 1Division of Clinical and Administrative Pharmacy, University of Iowa College of Pharmacy, Iowa City, Iowa 52242, USA. 2Department of Internal Medicine, University of Iowa College of Pharmacy, Iowa City, Iowa 52242, USA. 3Department of Neurology, University of Iowa College of Medicine, Iowa City, Iowa 52242, USATina HiselMasahiko KatoCatherine PesekMark DykenKrzysztof NarkiewiczVirend Somers
- Resource Type
- Journal article
- Publication Details
- Journal of hypertension, Vol.17(9), pp.1297-1300
- Publisher
- Lippincott Williams & Wilkins, Inc
- DOI
- 10.1097/00004872-199917090-00009
- PMID
- 10489107
- ISSN
- 0263-6352
- eISSN
- 1473-5598
- Language
- English
- Date published
- 09/1999
- Academic Unit
- Neurology
- Record Identifier
- 9984020877202771
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