Journal article
Recovery of Viable Bacteria from Probiotic Products that Target Oral Health
Probiotics and antimicrobial proteins, Vol.5(3), pp.227-231
09/01/2013
DOI: 10.1007/s12602-013-9142-2
PMCID: PMC3762494
PMID: 24015157
Abstract
Probiotic therapy has predominantly been directed toward promoting and maintaining intestinal health. In recent years, however, probiotic regimens that target oral health have appeared on the market. These regimens are often delivered in the form of lozenges. Despite the oral health claims made by the manufacturers of these products, there is little independent evidence in the literature to support such claims. In theory, probiotic organisms can be beneficial by several different means including direct inhibition of pathogens and boosting of the host immune response, with the underlying assumption that these mechanisms require a critical number of viable organisms. In this study, five brands of probiotics marketed for oral health were tested for the recovery of viable bacteria. For only one brand could viable bacteria be recovered within one log of the manufacturer's stated starting amount of bacteria. Nearly, a billion viable bacteria could be recovered from a lozenge of this brand. The other brands claimed similar starting amounts of bacteria at the time of manufacture but at least a three-log drop-off was observed in the amount of viable bacteria recovered from those products. Refrigeration of the probiotics significantly improved the recovery for one brand, but recoveries for all but one brand remained below the recommended daily dosage for probiotic regimens. It is concluded that probiotic brands differ significantly in the quantities of bacteria that remain viable with most failing to meet recommended dosage targets.
Details
- Title: Subtitle
- Recovery of Viable Bacteria from Probiotic Products that Target Oral Health
- Creators
- Jeffrey A. Banas - University of IowaEric T. Popp - University of Iowa
- Resource Type
- Journal article
- Publication Details
- Probiotics and antimicrobial proteins, Vol.5(3), pp.227-231
- Publisher
- Springer Nature
- DOI
- 10.1007/s12602-013-9142-2
- PMID
- 24015157
- PMCID
- PMC3762494
- ISSN
- 1867-1306
- eISSN
- 1867-1314
- Number of pages
- 5
- Grant note
- R21DE022605 / NATIONAL INSTITUTE OF DENTAL & CRANIOFACIAL RESEARCH; United States Department of Health & Human Services; National Institutes of Health (NIH) - USA; NIH National Institute of Dental & Craniofacial Research (NIDCR) R21 DE022605 / NIDCR NIH HHS; United States Department of Health & Human Services; National Institutes of Health (NIH) - USA; NIH National Institute of Dental & Craniofacial Research (NIDCR)
- Language
- English
- Date published
- 09/01/2013
- Academic Unit
- Pediatric Dentistry; Dental Research
- Record Identifier
- 9984367727402771
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