Journal article
Recurrent Cutibacterium acnes prosthetic valve endocarditis
BMJ case reports, Vol.14(7), p.e243878
07/29/2021
DOI: 10.1136/bcr-2021-243878
PMCID: PMC8323374
PMID: 34326116
Abstract
A 29-year-old man with a history of congenital aortic stenosis and mechanical aortic valve replacement with previous Cutibacterium acnes prosthetic valve endocarditis (PVE) presented with a 2-week history of fevers and night sweats. Transoesophageal echocardiogram revealed a 0.6 cm×0.5 cm vegetation on the mechanical aortic valve. An anaerobic blood culture became positive for C. acnes 6 days after the blood cultures were obtained. He did not have any surgical intervention. He was successfully treated with 6 weeks of ceftriaxone, followed by chronic suppression with oral doxycycline. Despite its low virulence, a growing number of C. acnes PVE cases have been reported, owing to its biofilm production. When clinical suspicion is high, extending culture incubation duration beyond the standard 5 days might be helpful. Most cases are treated with surgical repair or replacement in conjunction with antibiotics, but medical therapy alone has been documented as being successful.
Details
- Title: Subtitle
- Recurrent Cutibacterium acnes prosthetic valve endocarditis
- Creators
- Ahmed Ashraf Abdelhamid - University of Iowa Hospitals and ClinicsTakaaki Kobayashi - University of IowaJoseph Tholany - University of IowaPoorani Sekar - University of Iowa Hospitals and Clinics
- Resource Type
- Journal article
- Publication Details
- BMJ case reports, Vol.14(7), p.e243878
- DOI
- 10.1136/bcr-2021-243878
- PMID
- 34326116
- PMCID
- PMC8323374
- ISSN
- 1757-790X
- eISSN
- 1757-790X
- Language
- English
- Date published
- 07/29/2021
- Academic Unit
- Infectious Diseases; Internal Medicine
- Record Identifier
- 9984359797502771
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