Journal article
Recurrent Right Atrial Thrombus After Percutaneous ASD Closure
JACC. Case reports, Vol.30(33), 105591
10/22/2025
DOI: 10.1016/j.jaccas.2025.105591
PMCID: PMC12789738
PMID: 41136043
Abstract
Background: Percutaneous device closure is the preferred approach for closing secundum atrial septal defects (ASDs), offering a minimally invasive alternative to surgery. Although generally safe, device-related thrombus formation is a rare but serious complication, with limited evidence guiding diagnosis and management. Case Summary: We present a case of a 35-year-old woman who underwent percutaneous device closure of a secundum ASD. She developed intermittent fevers within 48 hours postprocedure, though initial work-up was negative. Three months later, a routine transthoracic echocardiogram revealed a mobile mass attached to the ASD device. She underwent AngioVac thrombectomy, but recurrence of thrombus required surgical removal of the device and ASD patch closure. Discussion: This case highlights a rare but serious complication of ASD device closure, underscoring the importance of vigilant follow-up and individualized antithrombotic strategies. Take-Home Messages: Recurrent thrombus formation after ASD device closure is rare but may necessitate surgical intervention in high-risk patients. Individualized risk assessment, including prothrombotic states and residual shunting, should guide postprocedural antithrombotic strategies.
Details
- Title: Subtitle
- Recurrent Right Atrial Thrombus After Percutaneous ASD Closure
- Creators
- Hidemi Kajimoto - University of Iowa, Iowa City, IA, United StatesGrant Burch - Oregon Health & Science UniversityCastigliano M. Bhamidipati - Oregon Health & Science UniversityColter Wichern - Oregon Health & Science UniversityKatie Lutz - Oregon Health & Science UniversityJeffrey A. Marbach - Oregon Health & Science UniversityKristina Wakeman - Oregon Health & Science UniversityLidija B. McGrath - Oregon Health & Science University
- Resource Type
- Journal article
- Publication Details
- JACC. Case reports, Vol.30(33), 105591
- DOI
- 10.1016/j.jaccas.2025.105591
- PMID
- 41136043
- PMCID
- PMC12789738
- NLM abbreviation
- JACC Case Rep
- ISSN
- 2666-0849
- eISSN
- 2666-0849
- Publisher
- Elsevier
- Language
- English
- Date published
- 10/22/2025
- Academic Unit
- Cardiology; Stead Family Department of Pediatrics
- Record Identifier
- 9985014816302771
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