Journal article
Recurrent neuroendocrine (merkel cell) carcinoma of the skin presenting as marrow failure in a man with systemic lupus erythematosus
Medical and pediatric oncology, Vol.21(2), pp.137-141
1993
DOI: 10.1002/mpo.2950210211
PMID: 8433681
Abstract
Neuroendocrine carcinoma of the skin, Merkel cell carcinoma, is an aggressive malignancy with a high incidence of local recurrence and metastasis. We describe a case of neuroendocrine carcinoma of the skin with unusual metastatic spread to the bone marrow in a 55-year-old man with systemic lupus erythematosus. Following resection of a left temporal subcutaneous nodule and complete left parotidectomy and radical lymph node dissection, the patient presented with pancytopenia. Although focal bony metastatic disease was not identified, his bone marrow was diffusely replaced by metastatic carcinoma. High-dose chemotherapy allowed a brief remission; however, the patient subsequently died with central nervous system metastases.
Details
- Title: Subtitle
- Recurrent neuroendocrine (merkel cell) carcinoma of the skin presenting as marrow failure in a man with systemic lupus erythematosus
- Creators
- Steven R Lentz - Departments of Medicine and Pathology, Washington University School of Medicine, St. Louis, MissouriLaurel Krewson - Departments of Medicine and Pathology, Washington University School of Medicine, St. Louis, MissouriMary M Zutter - Departments of Medicine and Pathology, Washington University School of Medicine, St. Louis, Missouri
- Resource Type
- Journal article
- Publication Details
- Medical and pediatric oncology, Vol.21(2), pp.137-141
- Publisher
- Wiley Subscription Services, Inc., A Wiley Company
- DOI
- 10.1002/mpo.2950210211
- PMID
- 8433681
- ISSN
- 0098-1532
- eISSN
- 1096-911X
- Number of pages
- 5
- Language
- English
- Date published
- 1993
- Academic Unit
- Hematology, Oncology, and Blood & Marrow Transplantation; Internal Medicine
- Record Identifier
- 9984094777102771
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