Journal article
Recurrent toxin-mediated perineal erythema
Archives of dermatological research = Archiv für dermatologische Forschung., Vol.132(1), pp.57-60
01/1996
DOI: 10.1001/archderm.1996.03890250067011
PMID: 8546484
Abstract
Background: Important new diseases due to bacterial toxins functioning as superantigens have been described with increasing frequency within recent years. Toxic shock syndrome, recalcitrant erythematous desquamating disorder, streptococcal toxic shock-like syndrome, and, most recently, mucocutaneous lymph node syndrome (Kawasaki disease) have been etiologically linked with certain staphylococcal and streptococcal toxins. We describe two patients with a novel clinical presentation of toxin-mediated disease, which shares certain clinical features with mucocutaneous lymph node syndrome.
Observations: Two otherwise healthy young male adults developed recurrent erysipelaslike perineal erythema, which regularly erupted within 1 to 2 days of the onset of acute pharyngitis. Accompanying signs included mucosal changes and acral erythema with desquamation. Throat cultures obtained during the acute episodes yielded toxin-producing Staphylococcus aureus from one patient and toxin-producing Streptococcus pyogenes from the other.
Conclusion: The recurrent nature, age predilection, and clinical presentation suggest that our patients display a unique clinical syndrome due to toxin-producing bacteria.(Arch Dermatol. 1996;132:57-60)
Details
- Title: Subtitle
- Recurrent toxin-mediated perineal erythema
- Creators
- Steven M MandersWarren R HeymannErcem AtillasoyJeffrey KleemanPatrick M Schlievert - University of Iowa, Microbiology and Immunology
- Resource Type
- Journal article
- Publication Details
- Archives of dermatological research = Archiv für dermatologische Forschung., Vol.132(1), pp.57-60
- DOI
- 10.1001/archderm.1996.03890250067011
- PMID
- 8546484
- ISSN
- 0340-3696
- eISSN
- 1432-069X
- Date published
- 01/1996
- Academic Unit
- Internal Medicine; Microbiology and Immunology
- Record Identifier
- 9984001790402771
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