Journal article
Red man syndrome caused by vancomycin powder
Journal of clinical neuroscience, Vol.50, pp.149-150
02/01/2018
DOI: 10.1016/j.jocn.2018.01.044
PMID: 29398192
Abstract
Red man syndrome (RMS) is a well-known hypersensitivity reaction caused by intravenous administration of vancomycin, with symptoms ranging from flushing, erythematous rash, pruritus, mild to profound hypotension, and even cardiac arrest. RMS has not previously been described from local application of vancomycin powder in a surgical wound, a technique increasingly utilized for infection prophylaxis in many surgical disciplines including neurosurgery. We describe the first reported case of RMS as a result of local intra-wound application of vancomycin powder for infection prophylaxis. A 73-year-old male with a history of Parkinson's disease underwent 2-stage deep brain stimulation implantation surgeries. Vancomycin powder was applied locally in the surgical wounds for infection prophylaxis during both of the surgeries. The patient developed a well-demarcated, geometric erythematous pruritic rash following the second surgery that was clinically diagnosed as RMS and resolved without sequelae.
Details
- Title: Subtitle
- Red man syndrome caused by vancomycin powder
- Creators
- Yasunori Nagahama - Department of Neurosurgery, University of Iowa Hospitals and Clinics, Iowa City, IA, USA. Electronic address: yasunori-nagahama@uiowa.eduMarta J VanBeek - Department of Dermatology, University of Iowa Hospitals and Clinics, Iowa City, IA, USAJeremy D W Greenlee - Department of Neurosurgery, University of Iowa Hospitals and Clinics, Iowa City, IA, USA
- Resource Type
- Journal article
- Publication Details
- Journal of clinical neuroscience, Vol.50, pp.149-150
- Publisher
- Scotland
- DOI
- 10.1016/j.jocn.2018.01.044
- PMID
- 29398192
- ISSN
- 0967-5868
- eISSN
- 1532-2653
- Language
- English
- Date published
- 02/01/2018
- Academic Unit
- Dermatology; Stead Family Department of Pediatrics; Iowa Neuroscience Institute; Neurosurgery; Otolaryngology
- Record Identifier
- 9984025308002771
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