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Redox sensing and histidine oxidation: no longer PerR-fect strangers
Journal article   Peer reviewed

Redox sensing and histidine oxidation: no longer PerR-fect strangers

W Scott Moye-Rowley
Nature chemical biology, Vol.2(5), pp.234-235
05/2006
DOI: 10.1038/nchembio0506-234
PMID: 16619021

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Abstract

Oxidation of cysteine residues is a well-described means of sensing oxidative stress. Analysis of a bacterial transcriptional repressor protein indicates that metal-catalyzed oxidation of histidine residues can provide oxidative stress control in a cysteine-independent fashion.

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