Reduced Attention in Former Smokers with and without COPD

Anna Croghan; Amanda Brunette; Kristen E Holm; Elizabeth Kozora; David J Moser; Frederick S Wamboldt; Kimberly Meschede; Barry J Make; James D Crapo; Howard D Weinberger; Kerrie L Moreau; Russell P Bowler; Karin F Hoth

doi:10.1007/s12529-019-09826-y

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Reduced Attention in Former Smokers with and without COPD

Journal article

Open access

Peer reviewed

Reduced Attention in Former Smokers with and without COPD

Anna Croghan, Amanda Brunette, Kristen E Holm, Elizabeth Kozora, David J Moser, Frederick S Wamboldt, Kimberly Meschede, Barry J Make, James D Crapo, Howard D Weinberger, …

International journal of behavioral medicine, Vol.26(6), pp.600-607

12/2019

DOI: 10.1007/s12529-019-09826-y

PMCID: PMC7269072

PMID: 31732904

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https://www.ncbi.nlm.nih.gov/pmc/articles/7269072View

Open Access

Abstract

Attention difficulties are often reported by patients with chronic obstructive pulmonary disease (COPD); however, limited research exists using objective tests designed specifically to measure attention in this population. This study aimed to (1) identify specific attention deficits in COPD and (2) determine which demographic/clinical characteristics are associated with reduced attention. Eighty-four former smokers (53 COPD, 31 no COPD) completed questionnaires, pulmonary function testing, and the Conner's Continuous Performance Test II (CPT-II). Participants with and without COPD were compared on CPT-II measures of inattention, impulsivity, and vigilance. CPT-II measures that differed significantly between the two groups were further examined using hierarchical regression modeling. Demographic/clinical characteristics were entered into models with attention as the dependent variable. Participants with COPD performed worse than those without COPD on CPT measures of inattention and impulsivity (i.e., detectability [discrimination of target from non-target stimuli], perseverations [reaction time under 100 ms], omissions [target stimuli response failures], and commissions [responses to non-target stimuli]). More severe COPD (measured by greater airflow limitation) was associated with poorer ability to detect targets vs. foils and perseverative responding after adjusting for age and other covariates in the model. Former smokers with COPD experience problems with attention that go beyond slowed processing speed, including aspects of inattention and impulsivity. Clinicians should be aware that greater airflow limitation and older age are associated with attention difficulties, as this may impact functioning.

Severity of Illness Index

Age Factors

Humans

Middle Aged

Attention

Male

Lung - physiopathology

Pulmonary Disease, Chronic Obstructive - physiopathology

Pulmonary Disease, Chronic Obstructive - psychology

Smoking - physiopathology

Female

Aged

Respiratory Function Tests

Smokers - psychology

Smoking - psychology

Details

Title: Subtitle: Reduced Attention in Former Smokers with and without COPD
Creators: Anna Croghan - Department of Psychiatry, University of Iowa Carver College of Medicine, 200 Hawkins Dr., W278GH, Iowa City, IA, 52242, USA
Amanda Brunette - Department of Psychological and Brain Sciences, University of Iowa, Iowa City, IA, USA
Kristen E Holm - Colorado School of Public Health, Department of Community and Behavioral Health, Aurora, CO, USA
Elizabeth Kozora - Department of Psychiatry, University of Colorado School of Medicine at the Anschutz Medical Campus, Aurora, CO, USA
David J Moser - Department of Psychiatry, University of Iowa Carver College of Medicine, 200 Hawkins Dr., W278GH, Iowa City, IA, 52242, USA
Frederick S Wamboldt - Department of Psychiatry, University of Colorado School of Medicine at the Anschutz Medical Campus, Aurora, CO, USA
Kimberly Meschede - National Jewish Health, Department of Medicine, Denver, CO, USA
Barry J Make - University of Colorado School of Medicine at the Anschutz Medical Campus, Aurora, CO, USA
James D Crapo - University of Colorado School of Medicine at the Anschutz Medical Campus, Aurora, CO, USA
Howard D Weinberger - University of Colorado School of Medicine at the Anschutz Medical Campus, Aurora, CO, USA
Kerrie L Moreau - VA Eastern Colorado Geriatric Research, Education, and Clinical Center Aurora, Denver, CO, USA
Russell P Bowler - University of Colorado School of Medicine at the Anschutz Medical Campus, Aurora, CO, USA
Karin F Hoth - Department of Psychiatry, University of Iowa Carver College of Medicine, 200 Hawkins Dr., W278GH, Iowa City, IA, 52242, USA. karin-hoth@uiowa.edu
Resource Type: Journal article
Publication Details: International journal of behavioral medicine, Vol.26(6), pp.600-607
DOI: 10.1007/s12529-019-09826-y
PMID: 31732904
PMCID: PMC7269072
NLM abbreviation: Int J Behav Med
ISSN: 1070-5503
eISSN: 1532-7558
Publisher: England
Grant note: UL1 TR001082 / NCATS NIH HHS R01 HL089897 / NHLBI NIH HHS K23 HL095658 / NHLBI NIH HHS R01 HL089856 / NHLBI NIH HHS NCT00608764 / COPD Foundation
Language: English
Date published: 12/2019
Academic Unit: Psychiatry; Iowa Neuroscience Institute; Medicine Administration
Record Identifier: 9984066379702771

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