Journal article
Reducing the burden of acute respiratory distress syndrome: the case for early intervention and the potential role of the emergency department
Shock (Augusta, Ga.), Vol.41(5), pp.378-387
05/2014
DOI: 10.1097/SHK.0000000000000142
PMCID: PMC4108587
PMID: 24469236
Abstract
The mortality for acute respiratory distress syndrome (ARDS) remains unacceptably high. Success in clinical trials has been limited, resulting in a lack of effective therapies to treat the syndrome. The projected increase in mechanically ventilated patients and global need for critical care services suggests that the clinical and research landscape in ARDS can no longer be confined to the intensive care unit (ICU). A demonstrable minority of patients present to the emergency department (ED) with ARDS, and ARDS onset typically occurs shortly after ICU admission. Furthermore, the ED is an entry point for many of the highest risk patients for ARDS development and progression. These facts, combined with prolonged lengths of stay in the ED, suggest that the ED could represent a window of opportunity for treatment and preventive strategies, as well as clinical trial enrollment. This review aims to discuss some of the potential strategies which may prevent or alter the trajectory of ARDS, with a focus on the potential role the ED could play in reducing the burden of this syndrome.
Details
- Title: Subtitle
- Reducing the burden of acute respiratory distress syndrome: the case for early intervention and the potential role of the emergency department
- Creators
- Brian M Fuller - Department of Anesthesiology Division of Critical Care Division of Emergency Medicine Washington University School of Medicine in St. LouisNicholas M Mohr - Department of Emergency Medicine Department of Anesthesiology Division of Critical Care Roy J. and Lucille A. Carver College of Medicine University of IowaRichard S Hotchkiss - Department of Anesthesiology Division of Critical Care Washington University School of Medicine in St. LouisMarin H Kollef - Department of Medicine Division of Pulmonary and Critical Care Medicine Washington University School of Medicine in St. Louis
- Resource Type
- Journal article
- Publication Details
- Shock (Augusta, Ga.), Vol.41(5), pp.378-387
- DOI
- 10.1097/SHK.0000000000000142
- PMID
- 24469236
- PMCID
- PMC4108587
- NLM abbreviation
- Shock
- ISSN
- 1073-2322
- eISSN
- 1540-0514
- Language
- English
- Date published
- 05/2014
- Academic Unit
- Epidemiology; Emergency Medicine; Anesthesia; Injury Prevention Research Center
- Record Identifier
- 9984025263402771
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