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Refined localization of the branchiootorenal syndrome gene by linkage and haplotype analysis
Journal article   Peer reviewed

Refined localization of the branchiootorenal syndrome gene by linkage and haplotype analysis

Li Ni, Michael J Wagner, William J Kimberling, Marcus E Pembrey, Kenneth M Grundfast, Shrawan Kumar, Stephen P Daiger, Dan E Wells, Kristin Johnson and Richard J. H Smith
American journal of medical genetics, Vol.51(2), pp.176-184
06/01/1994
DOI: 10.1002/ajmg.1320510222
PMID: 8092199

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Abstract

Branchiootorenal (BOR) syndrome is a common autosomal dominant form of hearing impairment previously mapped to 8q. This report refines the localization of the BOR syndrome gene by haplotype analysis to the interval flanked by markers D8S553 and D8S286. By multipoint linkage analysis, the disease locus most likely is flanked by markers D8S530 and D8S279. © 1994 Wiley‐Liss, Inc.

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