Journal article
Regional Myocardial Blood Flow in Man During Dipyridamole Coronary Vasodilation
Chest, Vol.87(6), pp.735-739
06/1985
DOI: 10.1378/chest.87.6.735
PMID: 3996059
Abstract
Regional myocardial blood flow before and after intravenous dipyridamole (0.56 mg/kg) was measured during cardiac catheterization in 11 patients using the 133Xe washout technique. Significant increases in heart rate (75 ± 4 vs 87 ± 6, p<0.004) and decreases in systolic blood pressure (144±8 vs 131 ± 7, p<0.02) were observed with dipyridamole infusion. However, double product and cardiac output did not differ before or after drug infusion. Regional myocardial blood flow increased from 67±3 (SEM) to 117 ± 3 ml/100 mg/min in myocardial segments supplied by nonobstructed coronary arteries. In stenotic coronary arteries, flow increased from 57 ± 5 to 79 ± 9 ml/100 mg/min with dipyridamole. We conclude that dipyridamole infusion results in flow differences which discriminate stenotic from nonstenotic coronary arteries
Details
- Title: Subtitle
- Regional Myocardial Blood Flow in Man During Dipyridamole Coronary Vasodilation
- Creators
- Sherman G. Sorensen - The University of Texas Health Science Center at San AntonioBertron M. Groves - The University of Texas Health Science Center at San AntonioLawrence D. Horwitz - The University of Texas Health Science Center at San AntonioTuhin K. Chaudhuri - The University of Texas Health Science Center at San Antonio
- Resource Type
- Journal article
- Publication Details
- Chest, Vol.87(6), pp.735-739
- Publisher
- Elsevier Inc
- DOI
- 10.1378/chest.87.6.735
- PMID
- 3996059
- ISSN
- 0012-3692
- eISSN
- 1931-3543
- Language
- English
- Date published
- 06/1985
- Academic Unit
- Cardiovascular Medicine; Internal Medicine
- Record Identifier
- 9984656532802771
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