Journal article
Regional cerebral blood flow changes during visually induced subjective sadness in healthy elderly persons
The journal of neuropsychiatry and clinical neurosciences, Vol.15(1), pp.35-44
2003
DOI: 10.1176/jnp.15.1.35
PMID: 12556569
Abstract
This study examined regional cerebral blood flow (rCBF) changes associated with visually induced sad affect in healthy elderly persons. Subjects viewed sadness-laden, happiness-laden, and emotionally neutral image sets while rCBF was recorded using [(15)O] water PET. The sad image set included human faces and scenery/objects ("scenes"). To control for secondary sensory processing, the neutral and happy comparison sets included exclusively either human faces or scenes. During the sad condition, the ventral prefrontal and temporal cortices were more active compared with happy and neutral scenes conditions and the thalamus was more active compared with happy and neutral faces conditions. Ventral prefrontal cortex and thalamus were associated with processing of sad visual stimuli, whether compared with neutral or happy stimuli. The specific findings associated with sad affect were contingent on the comparison stimuli content (scenes or human faces), not affect (i.e., comparison with neutral or happy conditions).
Details
- Title: Subtitle
- Regional cerebral blood flow changes during visually induced subjective sadness in healthy elderly persons
- Creators
- Sergio PARADISO - Department of Psychiatry, Department of Radiology, and PET Center, University of Iowa College of Medicine, Iowa City, IA, United StatesRobert G ROBINSON - Department of Psychiatry, Department of Radiology, and PET Center, University of Iowa College of Medicine, Iowa City, IA, United StatesLaura L BOLES PONTO - Department of Psychiatry, Department of Radiology, and PET Center, University of Iowa College of Medicine, Iowa City, IA, United StatesG. Leonard WATKINS - Department of Psychiatry, Department of Radiology, and PET Center, University of Iowa College of Medicine, Iowa City, IA, United StatesRichard D HICHWA - Department of Psychiatry, Department of Radiology, and PET Center, University of Iowa College of Medicine, Iowa City, IA, United States
- Resource Type
- Journal article
- Publication Details
- The journal of neuropsychiatry and clinical neurosciences, Vol.15(1), pp.35-44
- Publisher
- American Psychiatric Press; Washington, DC
- DOI
- 10.1176/jnp.15.1.35
- PMID
- 12556569
- ISSN
- 0895-0172
- eISSN
- 1545-7222
- Language
- English
- Date published
- 2003
- Academic Unit
- Radiology; Psychiatry; Research Administration; Pharmaceutical Sciences and Experimental Therapeutics; Physics and Astronomy; Radiation Oncology
- Record Identifier
- 9984051891402771
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