Journal article
Regional distribution of wall thickness and failure properties of human abdominal aortic aneurysm
Journal of biomechanics, Vol.39(16), pp.3010-3016
2006
DOI: 10.1016/j.jbiomech.2005.10.021
PMID: 16337949
Abstract
The regional distribution of wall thickness and failure properties in human abdominal aortic aneurysm (AAA) was explored. Three unruptured and one ruptured AAA were harvested as a whole during necropsy. Thickness was measured at about every 1.5
cm
2 wall surface area for an average of 100 measurement sites per AAA. Multiple longitudinally oriented rectangular specimen strips were cut at various locations from each AAA for a total of 48 strips. The strips were subjected to uniaxial extension until failure. Wall thickness varied regionally and between AAA from as low as 0.23
mm at a rupture site to 4.26
mm at a calcified site (median=1.48
mm). Wall thickness was slightly lower in the posterior and right regions. The failure tension (ultimate) of specimen strips varied regionally and between AAA from 5.5
N/cm close to a blister site in the ruptured AAA to 42.3
N/cm at the undilated neck of a 4
cm diameter unruptured AAA (median=14.8
N/cm). Failure stress (ultimate) varied from 33.6 to 235.1
N/cm
2 (median=126.6
N/cm
2). There was no perceptible pattern in failure properties along the circumference. Failure tension of specimen strips at or close to blisters was mostly low. The rupture site in the ruptured aneurysm had the lowest recorded wall thickness of 0.23
mm with only slightly higher readings within a 1
cm radius. The failure tension of the specimen strip close to the rupture site was low (11.1 N/cm) compared to its neighborhood in the ruptured aneurysm.
Details
- Title: Subtitle
- Regional distribution of wall thickness and failure properties of human abdominal aortic aneurysm
- Creators
- Madhavan L Raghavan - Biomedical Engineering, University of Iowa, 1422 Seamans Center, Iowa City, IA 52242, USAJarin Kratzberg - Biomedical Engineering, University of Iowa, 1422 Seamans Center, Iowa City, IA 52242, USAErasmo Magalhães Castro de Tolosa - Department of Surgery, University of São Paulo Medical School, SP, BrazilMauro M Hanaoka - Department of Surgery, University of São Paulo Medical School, SP, BrazilPatricia Walker - Biomedical Engineering, University of Iowa, 1422 Seamans Center, Iowa City, IA 52242, USAErasmo Simão da Silva - Department of Surgery, University of São Paulo Medical School, SP, Brazil
- Resource Type
- Journal article
- Publication Details
- Journal of biomechanics, Vol.39(16), pp.3010-3016
- Publisher
- Elsevier Ltd
- DOI
- 10.1016/j.jbiomech.2005.10.021
- PMID
- 16337949
- ISSN
- 0021-9290
- eISSN
- 1873-2380
- Language
- English
- Date published
- 2006
- Academic Unit
- Roy J. Carver Department of Biomedical Engineering
- Record Identifier
- 9984064581402771
Metrics
12 Record Views