Journal article
Regioselective ring-closing metathesis on terpenoid acrylates and acrylamides
Tetrahedron letters, Vol.42(35), pp.6069-6072
2001
DOI: 10.1016/S0040-4039(01)01179-0
Abstract
A series of acrylate esters was prepared by treatment of representative terpenoid aldehydes with allyl or vinyl magnesium bromide followed by reaction with acryloyl chloride. In all cases, ring-closing metathesis (RCM) resulted in regioselective formation of unsaturated lactones through metathesis of the acrylate and terminal olefins. After condensation of farnesal with a primary amine, a parallel series of reactions led to formation of the corresponding lactam. Graphic
Details
- Title: Subtitle
- Regioselective ring-closing metathesis on terpenoid acrylates and acrylamides
- Creators
- Yanming DuDavid F Wiemer
- Resource Type
- Journal article
- Publication Details
- Tetrahedron letters, Vol.42(35), pp.6069-6072
- Publisher
- Elsevier Ltd
- DOI
- 10.1016/S0040-4039(01)01179-0
- ISSN
- 0040-4039
- eISSN
- 1873-3581
- Language
- English
- Date published
- 2001
- Academic Unit
- Chemistry; Neuroscience and Pharmacology
- Record Identifier
- 9983985949702771
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