Regulating cytoskeleton-based vesicle motility

Heidi Hehnly; Mark Stamnes

doi:10.1016/j.febslet.2007.01.094

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Regulating cytoskeleton-based vesicle motility

Journal article

Peer reviewed

Regulating cytoskeleton-based vesicle motility

Heidi Hehnly and Mark Stamnes

FEBS letters, Vol.581(11), pp.2112-2118

05/22/2007

DOI: 10.1016/j.febslet.2007.01.094

PMCID: PMC1974873

PMID: 17335816

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https://www.ncbi.nlm.nih.gov/pmc/articles/1974873View

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Abstract

During vesicular transport, the assembly of the coat complexes and the selection of cargo proteins must be coordinated with the subsequent translocation of vesicles from the donor to an acceptor compartment. Here, we review recent progress toward uncovering the molecular mechanisms that connect transport vesicles to the protein machinery responsible for cytoskeleton-mediated motility. An emerging theme is that vesicle cargo proteins, either directly or through binding interactions with coat proteins, are able to influence cytoskeletal dynamics and motor protein function. Hence, a vesicle's cargo composition may help direct its intracellular motility and targeting. (C) 2007 Federation of European Biochemical Societies. Published by Elsevier B.V. All rights reserved.

Biochemistry & Molecular Biology

Biophysics

Cell Biology

Life Sciences & Biomedicine

Science & Technology

Details

Title: Subtitle: Regulating cytoskeleton-based vesicle motility
Creators: Heidi Hehnly - Roy J. and Lucille A. Carver College of Medicine
Mark Stamnes - Roy J. and Lucille A. Carver College of Medicine
Resource Type: Journal article
Publication Details: FEBS letters, Vol.581(11), pp.2112-2118
DOI: 10.1016/j.febslet.2007.01.094
PMID: 17335816
PMCID: PMC1974873
NLM abbreviation: FEBS Lett
ISSN: 1873-3468
eISSN: 1873-3468
Publisher: Wiley
Number of pages: 7
Grant note: R01GM068674 / NATIONAL INSTITUTE OF GENERAL MEDICAL SCIENCES; United States Department of Health & Human Services; National Institutes of Health (NIH) - USA; NIH National Institute of General Medical Sciences (NIGMS) R01 GM068674-04; R01 GM068674 / NIGMS NIH HHS; United States Department of Health & Human Services; National Institutes of Health (NIH) - USA; NIH National Institute of General Medical Sciences (NIGMS)
Language: English
Date published: 05/22/2007
Academic Unit: Molecular Physiology and Biophysics; Internal Medicine
Record Identifier: 9984297493602771

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