Journal article
Regulation of C-Type Lectin Receptor-Mediated Antifungal Immunity
Frontiers in immunology, Vol.9, pp.123-123
2018
DOI: 10.3389/fimmu.2018.00123
PMCID: PMC5799234
PMID: 29449845
Abstract
Of all the pathogen recognition receptor families, C-type lectin receptor (CLR)-induced intracellular signal cascades are indispensable for the initiation and regulation of antifungal immunity. Ongoing experiments over the last decade have elicited diverse CLR functions and novel regulatory mechanisms of CLR-mediated-signaling pathways. In this review, we highlight novel insights in antifungal innate and adaptive-protective immunity mediated by CLRs and discuss the potential therapeutic strategies against fungal infection based on targeting the mediators in the host immune system.
Details
- Title: Subtitle
- Regulation of C-Type Lectin Receptor-Mediated Antifungal Immunity
- Creators
- Juan Tang - Department of Nephrology, Xiangya Hospital, Central South University, Changsha, Hunan, ChinaGuoxin Lin - Department of Anesthesiology, The Third Xiangya Hospital, Central South University, Changsha, Hunan, ChinaWallace Y Langdon - School of Biological Sciences, University of Western Australia, Perth, WA, AustraliaLijian Tao - Department of Nephrology, Xiangya Hospital, Central South University, Changsha, Hunan, ChinaJian Zhang - Department of Pathology, The University of Iowa, Iowa City, IA, United States
- Resource Type
- Journal article
- Publication Details
- Frontiers in immunology, Vol.9, pp.123-123
- DOI
- 10.3389/fimmu.2018.00123
- PMID
- 29449845
- PMCID
- PMC5799234
- NLM abbreviation
- Front Immunol
- ISSN
- 1664-3224
- eISSN
- 1664-3224
- Publisher
- Switzerland
- Grant note
- R01 AI121196 / NIAID NIH HHS R01 AI123253 / NIAID NIH HHS R01 AI090901 / NIAID NIH HHS
- Language
- English
- Date published
- 2018
- Academic Unit
- Pathology
- Record Identifier
- 9984047670002771
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