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Regulation of RNA Polymerase II Elongation by c-Myc
Journal article   Open access   Peer reviewed

Regulation of RNA Polymerase II Elongation by c-Myc

David H Price
Cell (Cambridge), Vol.141(3), pp.399-400
04/30/2010
DOI: 10.1016/j.cell.2010.04.016
PMID: 20434979
url
https://doi.org/10.1016/j.cell.2010.04.016View
Published (Version of record) Open Access

Abstract

The genome-wide mapping presented in this issue by Rahl et al. (2010) demonstrates how the transcription factor c-Myc interfaces with the machinery that controls RNA polymerase II elongation. These findings account for the ability of c-Myc to activate the expression of a large number of genes that promote rapid proliferation.

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