Journal article
Regulation of exercise-induced fiber type transformation, mitochondrial biogenesis, and angiogenesis in skeletal muscle
Journal of applied physiology (1985), Vol.110(1), pp.264-274
01/2011
DOI: 10.1152/japplphysiol.00993.2010
PMCID: PMC3253006
PMID: 21030673
Abstract
Skeletal muscle exhibits superb plasticity in response to changes in functional demands. Chronic increases of skeletal muscle contractile activity, such as endurance exercise, lead to a variety of physiological and biochemical adaptations in skeletal muscle, including mitochondrial biogenesis, angiogenesis, and fiber type transformation. These adaptive changes are the basis for the improvement of physical performance and other health benefits. This review focuses on recent findings in genetically engineered animal models designed to elucidate the mechanisms and functions of various signal transduction pathways and gene expression programs in exercise-induced skeletal muscle adaptations.
Details
- Title: Subtitle
- Regulation of exercise-induced fiber type transformation, mitochondrial biogenesis, and angiogenesis in skeletal muscle
- Creators
- Zhen Yan - University of VirginiaMitsuharu Okutsu - University of VirginiaYasir N. Akhtar - University of VirginiaVitor A. Lira - University of Virginia
- Resource Type
- Journal article
- Publication Details
- Journal of applied physiology (1985), Vol.110(1), pp.264-274
- DOI
- 10.1152/japplphysiol.00993.2010
- PMID
- 21030673
- PMCID
- PMC3253006
- NLM abbreviation
- J Appl Physiol (1985)
- ISSN
- 8750-7587
- eISSN
- 1522-1601
- Language
- English
- Date published
- 01/2011
- Academic Unit
- Health, Sport, and Human Physiology
- Record Identifier
- 9984259398702771
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