Regulators of G protein signaling (RGS) proteins as drug targets: modulating G-protein-coupled receptor (GPCR) signal transduction

Journal article

Peer reviewed

David L Roman and John R Traynor

Journal of medicinal chemistry, Vol.54(21), pp.7433-7440

11/10/2011

DOI: 10.1021/jm101572n

PMCID: PMC3208131

PMID: 21916427

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no abstract

Signal Transduction

Ligands

RGS Proteins - genetics

Peptidomimetics - pharmacology

Antipsychotic Agents - adverse effects

Humans

Analgesics - administration & dosage

Receptors, G-Protein-Coupled - agonists

Molecular Targeted Therapy

Antiparkinson Agents - adverse effects

Antipsychotic Agents - administration & dosage

Animals

Drug Interactions

Receptors, G-Protein-Coupled - antagonists & inhibitors

RGS Proteins - metabolism

Antidepressive Agents - administration & dosage

Antiparkinson Agents - administration & dosage

RGS Proteins - antagonists & inhibitors

Antidepressive Agents - adverse effects

Oligopeptides - pharmacology

Analgesics - adverse effects

Receptors, G-Protein-Coupled - physiology

Title: Subtitle: Regulators of G protein signaling (RGS) proteins as drug targets: modulating G-protein-coupled receptor (GPCR) signal transduction
Creators: David L Roman - College of Pharmacy, The University of Iowa , Iowa City, IA 52242, USA
John R Traynor
Resource Type: Journal article
Publication Details: Journal of medicinal chemistry, Vol.54(21), pp.7433-7440
Publisher: United States
DOI: 10.1021/jm101572n
PMID: 21916427
PMCID: PMC3208131
ISSN: 0022-2623
eISSN: 1520-4804
Grant note: R01 DA004087-20 / NIDA NIH HHS R01 DA004087 / NIDA NIH HHS DA04087 / NIDA NIH HHS
Language: English
Date published: 11/10/2011
Academic Unit: Pharmacy; Iowa Neuroscience Institute; Pharmaceutical Sciences and Experimental Therapeutics; Medicinal and Natural Products Chemistry
Record Identifier: 9984065390802771

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