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Relapsing polychondritis in a child with familial Mediterranean fever and selective immunoglobulin a deficiency
Journal article

Relapsing polychondritis in a child with familial Mediterranean fever and selective immunoglobulin a deficiency

Gülay Demircin, Erdoğan Okur, Hazfa Uçur, Meltem Uğraş and Tolga Şen
International journal of pediatric otorhinolaryngology extra, Vol.7(3), pp.112-114
09/01/2012
DOI: 10.1016/j.pedex.2012.03.002

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Abstract

Relapsing polychondritis (RP) is a rare multisystem disease of unknown etiology characterized by recurrent and progressive course of destructive and inflammatory lesions of cartilage. Its association with familial Mediterranean fever (FMF) has been reported in only two adult cases. We present here a 13-year old girl with FMF and selective immunoglobulin (Ig) A deficiency who developed RP. To our knowledge, this case is the first well documented child and the third patient in the literature with FMF and RP together with selective Ig A deficiency which has not been reported with both disorders before.
Childhood Familial Mediterranean fever Relapsing polychondritis Selective immunoglobulin A deficiency

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