Journal article
Relation of serum uric acid to an exaggerated systolic blood pressure response to exercise testing in men with normotension
The journal of clinical hypertension (Greenwich, Conn.), Vol.20(3), pp.551-556
03/2018
DOI: 10.1111/jch.13219
PMCID: PMC8030753
PMID: 29457335
Abstract
The authors investigated the hypothesis that high serum uric acid concentrations may be related to an exaggerated systolic blood pressure (SBP) response to maximal exercise testing in men with normotension, independent of potential confounding variables. In 4640 healthy men with normotension who underwent maximal treadmill exercise testing and fasting blood chemistry studies, including serum uric acid concentrations, an exaggerated SBP response, defined as SBP ≥ 210 mm Hg, was detected in 152 men (3.3%). After adjusting for potential confounders, participants in the highest quartile of serum uric acid (>6.6 mg/dL) had a higher odds ratio of demonstrating an exaggerated SBP to maximal exercise (odds ratio, 2.19; 95% confidence interval, 1.24-3.86) compared with participants in the lowest quartile of serum uric acid (<5.1 mg/dL). High serum uric acid concentrations are associated with an exaggerated SBP response to maximal exercise testing in men with normotension, independent of established coronary risk factors.
Details
- Title: Subtitle
- Relation of serum uric acid to an exaggerated systolic blood pressure response to exercise testing in men with normotension
- Creators
- Sae Young Jae - University of SeoulKanokwan Bunsawat - University of Illinois Urbana-ChampaignYoon-Ho Choi - Sungkyunkwan UniversityYeon Soo Kim - Seoul National University of EducationRhian M Touyz - University of GlasgowJeong Bae Park - Dankook UniversityBarry A Franklin - Beaumont Hospital, Royal Oak
- Resource Type
- Journal article
- Publication Details
- The journal of clinical hypertension (Greenwich, Conn.), Vol.20(3), pp.551-556
- DOI
- 10.1111/jch.13219
- PMID
- 29457335
- PMCID
- PMC8030753
- NLM abbreviation
- J Clin Hypertens (Greenwich)
- ISSN
- 1524-6175
- eISSN
- 1751-7176
- Language
- English
- Date published
- 03/2018
- Academic Unit
- Health, Sport, and Human Physiology
- Record Identifier
- 9984948043302771
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