Journal article
Relation of temporal asymmetry during walking to 2-year knee pain outcomes in those with mild-to-moderate unilateral knee pain: an exploratory analysis from the Multicenter Osteoarthritis (MOST) Study
Arthritis care & research, Vol.75(8), pp.1735-1743
08/2023
DOI: 10.1002/acr.25050
PMCID: PMC10133409
PMID: 36305013
Abstract
OBJECTIVE We aimed to 1) explore the cross-sectional relation of unilateral knee pain severity and temporal asymmetry during walking and 2) determine relations of temporal asymmetry during walking to 2-year changes in ipsilateral and contralateral knee pain in those with mild-to-moderate unilateral knee pain. METHODS The Multicenter Osteoarthritis Study is a prospective cohort study of adults with or at risk for knee osteoarthritis. The current study included participants with unilateral knee pain. Gait was assessed during self-selected and fast walking at baseline. Knee pain was assessed at baseline and 2-years. We calculated limb symmetry indices (LSIs; non-painful limb/painful limb x 100) for stance, single limb support, and double limb support times then examined their relations to 1) unilateral knee pain severity, 2) incident contralateral knee pain, and 3) persistent ipsilateral knee pain. RESULTS Unilateral knee pain severity was not associated with temporal asymmetry during self-selected or fast walking. At 2-years, 17.1% had incident contralateral knee pain and 51.4% had persistent ipsilateral knee pain. For self-selected walking, greater LSIs (i.e., longer time on the non-painful limb) for stance and single limb support were associated with decreased odds of incident contralateral knee pain. Measures of temporal asymmetry were not associated with persistent ipsilateral knee pain, except for single limb support during fast walking. CONCLUSIONFor those with unilateral knee pain, temporal asymmetry during walking is not associated with pain severity. However, select measures of stance and single limb support during self-selected and fast walking relate to longitudinal knee pain outcomes. This article is protected by copyright. All rights reserved.
Details
- Title: Subtitle
- Relation of temporal asymmetry during walking to 2-year knee pain outcomes in those with mild-to-moderate unilateral knee pain: an exploratory analysis from the Multicenter Osteoarthritis (MOST) Study
- Creators
- Patrick Corrigan - Northeastern UniversityDavid T Felson - Boston UniversityCara L LewisTuhina Neogi - Boston UniversityMichael P LaValley - Boston UniversityK Doug Gross - MGH Institute of Health ProfessionsMichael C Nevitt - University of California, San FranciscoCora E Lewis - University of Alabama at BirminghamJames C Torner - University of IowaJoshua J Stefanik - Northeastern University
- Resource Type
- Journal article
- Publication Details
- Arthritis care & research, Vol.75(8), pp.1735-1743
- DOI
- 10.1002/acr.25050
- PMID
- 36305013
- PMCID
- PMC10133409
- NLM abbreviation
- Arthritis Care Res (Hoboken)
- ISSN
- 2151-464X
- eISSN
- 2151-4658
- Grant note
- DOI: 10.13039/100000069, name: National Institute of Arthritis and Musculoskeletal and Skin Diseases, award: K23AR070913, K24AR070892; DOI: 10.13039/100000049, name: National Institute on Aging, award: U01AG18820, U01AG18832, U01AG18947, U01AG19069; DOI: 10.13039/100000002, name: National Institutes of Health, award: P30AR072571; DOI: 10.13039/100006260, name: Rheumatology Research Foundation, award: Scientist Development Award
- Language
- English
- Electronic publication date
- 10/27/2022
- Date published
- 08/2023
- Academic Unit
- Neurology; Epidemiology; Injury Prevention Research Center; Neurosurgery
- Record Identifier
- 9984311559102771
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