Journal article
Relative Elastic Modulus Imaging Using Sector Ultrasound Data for Abdominal Applications: An Evaluation of Strategies and Feasibility
IEEE transactions on ultrasonics, ferroelectrics, and frequency control, Vol.63(9), pp.1432-1440
09/01/2016
DOI: 10.1109/TUFFC.2016.2589270
PMCID: PMC5291116
PMID: 27411219
Abstract
We reconstruct the elastic modulus distribution for one tissue mimicking (TM) phantom and two in vivo biopsyconfirmed liver tumors using curvilinear ultrasound echo data. Spatial distribution of the relative elastic modulus values is determined by solving an inverse problem within a region of interest (ROI). This inverse problem solution requires knowledge of the ultrasonically measured displacement field in a uniform rectilinear grid to ensure that the resolution on the resultant relative elastic modulus elastogram will be uniform over the entire ROI. Taking advantage of a new speckle tracking algorithm, two different displacement tracking strategies are investigated: 1) sector-shaped ultrasound data were converted to ultrasound data on a rectilinear grid prior to speckle tracking and 2) axial and lateral displacements directly obtained from sector-shaped data were converted to vertical and horizontal displacements on a rectilinear grid after speckle tracking. Compared with strain elastography (SE), TM phantom results show that relative elastic modulus imaging (REMI) using Strategy 2 provided higher contrast-to-noise ratios (>300% and 25% increases compared with SE and REMI using Strategy 1, respectively). Furthermore, in phantoms, REMI using Strategy 2 more accurately (a 1.3% difference to shear wave elastography measurements) estimated the elastic contrast ratio between the target and the background, compared with both SE (20%-25%) and REMI using Strategy 1 (4.1%). It was also observed that relative modulus elastograms were more consistent with anatomical structures visualized on corresponding B-mode images for the two in vivo liver cases. Overall, we conclude that applying REMI is feasible for abdominal organs such as the liver. Strategy 2 offered improved and consistent results for the data investigated.
Details
- Title: Subtitle
- Relative Elastic Modulus Imaging Using Sector Ultrasound Data for Abdominal Applications: An Evaluation of Strategies and Feasibility
- Creators
- Bo Peng - Southwest Petroleum UniversityYu Wang - Michigan Technological UniversityWenjun Yang - Univ Wisconsin, Dept Med Phys, 1530 Med Sci Ctr, Madison, WI 53706 USATomy Varghese - University of Wisconsin–MadisonJingfeng Jiang - Michigan Technological University
- Resource Type
- Journal article
- Publication Details
- IEEE transactions on ultrasonics, ferroelectrics, and frequency control, Vol.63(9), pp.1432-1440
- DOI
- 10.1109/TUFFC.2016.2589270
- PMID
- 27411219
- PMCID
- PMC5291116
- NLM abbreviation
- IEEE Trans Ultrason Ferroelectr Freq Control
- ISSN
- 0885-3010
- eISSN
- 1525-8955
- Publisher
- IEEE
- Number of pages
- 9
- Grant note
- R01-CA112192; R15-CA179409 / US NIH/NCI; United States Department of Health & Human Services; National Institutes of Health (NIH) - USA; NIH National Cancer Institute (NCI) Chinese Scholarship Council; China Scholarship Council R15CA179409 / NATIONAL CANCER INSTITUTE; United States Department of Health & Human Services; National Institutes of Health (NIH) - USA; NIH National Cancer Institute (NCI)
- Language
- English
- Date published
- 09/01/2016
- Academic Unit
- Radiation Oncology
- Record Identifier
- 9984697641502771
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