Journal article
Reliability and validity of blood pressure measurement in the Secondary Prevention of Small Subcortical Strokes study
Blood pressure monitoring, Vol.12(1), pp.1-8
02/2007
DOI: 10.1097/MBP.0b013e3280858d5b
PMCID: PMC3970705
PMID: 17303981
Abstract
RATIONALE: The Secondary Prevention of Small Subcortical Strokes study is a multicenter, international trial funded by the National Institutes of Health testing the role of lowering systolic blood pressure to <130 mmHg in the prevention of stroke recurrence and cognitive decline in patients with recent symptomatic small subcortical stroke. Reliable and unbiased blood pressure measurement is critical to successful completion of the trial. METHODS: We looked at the reliability and validity of both the device used for blood pressure measurement and observer performance during measurement to assess the quality of blood pressure determination in the study. The Colin 8800C blood pressure device was tested for performance to Association for the Advancement of Medical Instrumentation standards and for presence of skipped digits. Observer performance was tested by examining adherence to the Secondary Prevention of Small Subcortical Strokes protocol. RESULTS: The mean difference (in mmHg) between the Colin device and the average of the two observers was 3.9 (SD 6.7) and -2.1 (SD 6.1) for systolic and diastolic pressures respectively, thereby meeting Association for the Advancement of Medical Instrumentation requirements. No skipped digits were found between 82-230 and 40-120 mmHg for systolic and diastolic pressures, respectively. Observer performance was excellent with greater than 90% of patients having blood pressure measured consistently according to the protocol. CONCLUSIONS: Device and observer performance in Secondary Prevention of Small Subcortical Strokes is excellent. Interpretation of the Secondary Prevention of Small Subcortical Strokes data for the effect of lowering systolic blood pressure on patient outcomes will not likely be adversely affected by these factors. Accuracy will be monitored throughout the remainder of the trial to ensure that this high quality is maintained. © 2007 Lippincott Williams & Wilkins, Inc.
Details
- Title: Subtitle
- Reliability and validity of blood pressure measurement in the Secondary Prevention of Small Subcortical Strokes study
- Creators
- Pablo E Pérgola - The University of Texas Health Science Center at San AntonioCarole L White - University of Alabama at BirminghamJohn W Graves - Mayo ClinicChristopher S Coffey - University of Alabama at BirminghamSilvina B Tonarelli - The University of Texas Health Science Center at San AntonioRobert G Hart - The University of Texas Health Science Center at San AntonioOscar R Benavente - The University of Texas Health Science Center at San Antonio
- Contributors
- SPS3 Investigators (Author)
- Resource Type
- Journal article
- Publication Details
- Blood pressure monitoring, Vol.12(1), pp.1-8
- DOI
- 10.1097/MBP.0b013e3280858d5b
- PMID
- 17303981
- PMCID
- PMC3970705
- NLM abbreviation
- Blood Press Monit
- ISSN
- 1359-5237
- eISSN
- 1473-5725
- Language
- English
- Date published
- 02/2007
- Academic Unit
- Biostatistics
- Record Identifier
- 9984227043602771
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