Journal article
Reliability of a new scoring system for intraarticular mineralization of the knee: Boston University Calcium Knee Score (BUCKS)
Osteoarthritis and cartilage, Vol.28(6), pp.802-810
06/2020
DOI: 10.1016/j.joca.2020.03.003
PMCID: PMC8188576
PMID: 32173626
Abstract
The role of intra-articular mineralization in osteoarthritis (OA) is unclear. Its understanding may potentially advance our knowledge of knee OA pathogenesis. We describe and assess the reliability of a novel computed tomography (CT) scoring system, the Boston University Calcium Knee Score (BUCKS) for evaluating intra-articular mineralization.
We included subjects from the most recent study visit of the Multicenter Osteoarthritis Study (MOST) Study, a NIH-funded longitudinal cohort of community-dwelling older adults with or at risk of knee OA. All subjects underwent CT of bilateral knees. Each knee was scored at 28 scored locations (14 for cartilage, 6 for menisci, 6 for ligaments, 1 for joint capsule, and 1 popliteal-tibial vessels). A single musculoskeletal radiologist scored cartilage and meniscus subregions, as well as vascular calcifications assigning to each a score ranging from 0 to 3. The joint capsule, medial and lateral posterior meniscal roots, anterior cruciate ligament (ACL)/posterior cruciate ligament (PCL) and 2 collateral ligaments [medial collateral ligament (MCL)/lateral collateral ligament (LCL)] were each scored 0 or 1 for absence or presence of mineralization. To assess reliability, 31 subject CTs were reread 12 weeks later by the same reader and by a second reader and agreement was evaluated using a weighted kappa.
The intra-reader reliability ranged from 0.92 for ligaments to 1.0 for joint capsule. The inter-reader reliability ranged from 0.94 for cartilage and ligaments, to 1.0 for joint capsule.
BUCKS demonstrated excellent reliability and is a potentially useful CT-based tool for studying the role of calcium crystals in knee OA.
Details
- Title: Subtitle
- Reliability of a new scoring system for intraarticular mineralization of the knee: Boston University Calcium Knee Score (BUCKS)
- Creators
- A Guermazi - Department of Radiology, Boston University School of Medicine, Boston University, Boston, MA, USAM Jarraya - Department of Radiology, Boston University School of Medicine, Boston University, Boston, MA, USAJ.A Lynch - Department of Epidemiology, University of California San Francisco, CA, USAD.T Felson - Department of Medicine, Boston University School of Medicine, Boston University, Boston, MA, USAM Clancy - Department of Medicine, Boston University School of Medicine, Boston University, Boston, MA, USAM Nevitt - Department of Epidemiology, University of California San Francisco, CA, USAC.E Lewis - Department of Epidemiology, University of Alabama at Birmingham, AL, USAJ Torner - Department of Epidemiology, College of Public Health, University of Iowa, IA, USAT Neogi - Department of Medicine, Boston University School of Medicine, Boston University, Boston, MA, USA
- Resource Type
- Journal article
- Publication Details
- Osteoarthritis and cartilage, Vol.28(6), pp.802-810
- DOI
- 10.1016/j.joca.2020.03.003
- PMID
- 32173626
- PMCID
- PMC8188576
- NLM abbreviation
- Osteoarthritis Cartilage
- ISSN
- 1063-4584
- eISSN
- 1522-9653
- Publisher
- Elsevier Ltd
- Grant note
- DOI: 10.13039/100000002, name: National Institutes of Health, award: U01-AG-19069, P60 AR047785, U01-AG-18947, K24 AR070892, U01-AG-18832, U01-AG-18820; DOI: 10.13039/100000049, name: National Institute on Aging, award: U01-AG-19069, P60 AR047785, U01-AG-18947, K24 AR070892, U01-AG-18832, U01-AG-18820
- Language
- English
- Date published
- 06/2020
- Academic Unit
- Epidemiology; Surgery; Injury Prevention Research Center; Neurosurgery
- Record Identifier
- 9984214815502771
Metrics
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