Journal article
Renal Medullary Carcinoma: The Zebra Amongst the Horses
Urology (Ridgewood, N.J.), Vol.187, pp.78-81
05/01/2024
DOI: 10.1016/j.urology.2024.02.048
PMID: 38467288
Abstract
A 13-year old Latino male presented with recurrent gross hematuria, 5 cm right-sided poorly defined heterogeneous mass, enlarged retrocaval lymph nodes, and 1.2 cm paratracheal lymph node. Given the need for multiple blood transfusions, robot-assisted radical nephrectomy with lymph node dissection was performed. Pathology revealed pT3a high-grade tumor, clear margins, and positive lymph node. Additionally, with multiple sickled RBCs and loss of staining of SMARCB1 in tumor specimen, and hemoglobin electrophoresis suggesting sickle cell trait, diagnosis of metastatic renal medullary carcinoma was confirmed. The patient was enrolled into COG AREN 03B2 trial, and has completed 10 cycles of carboplatin/gemcitabine/bortezomib alternating with cisplatin/gemcitabine/paclitaxel, with no evidence of recurrent disease 9 months post-surgery. UROLOGY 187: 78-81, 2024. (c) 2024 Elsevier Inc. All rights reserved.
Details
- Title: Subtitle
- Renal Medullary Carcinoma: The Zebra Amongst the Horses
- Creators
- Deepansh Dalela - The University of Texas Southwestern Medical CenterShane Batie - The University of Texas Southwestern Medical CenterAlexandra Carolan - The University of Texas Southwestern Medical CenterBruce Schlomer - The University of Texas Southwestern Medical CenterRebecca Collins - Southwestern Medical CenterMicah Jacobs - Southwestern Medical Center
- Resource Type
- Journal article
- Publication Details
- Urology (Ridgewood, N.J.), Vol.187, pp.78-81
- DOI
- 10.1016/j.urology.2024.02.048
- PMID
- 38467288
- NLM abbreviation
- Urology
- ISSN
- 0090-4295
- eISSN
- 1527-9995
- Publisher
- Elsevier
- Number of pages
- 4
- Language
- English
- Date published
- 05/01/2024
- Academic Unit
- Urology
- Record Identifier
- 9984949453602771
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