Journal article
Renal Transplantation After Streptococcus pneumoniae-Associated Hemolytic Uremic Syndrome
American journal of kidney diseases, Vol.37(2), pp.e15.1-e15.8
02/2001
DOI: 10.1053/ajkd.2001.21359
PMID: 11157401
Abstract
Of the several causes of nondiarrheal hemolytic uremic syndrome (HUS), infection with Streptococcus pneumoniae is infrequent, but important, because of its unique pathogenesis. A comprehensive literature review found 37 well-documented cases of S pneumoniae-associated HUS (SP-HUS), only 2 of which progressed to end-stage renal disease (ESRD). We report the third such child, and the first to receive a renal transplant following SP-HUS. Her course illustrates several unique characteristics of SP-HUS common to previous patients reported in the literature, including a greater duration of oligoanuria compared with cases not progressing to ESRD, the significant adverse effect of unwashed blood products, and a possible influence of female gender on outcome. Clinicians caring for children with SP-HUS should be aware of these differences and modify therapy appropriately to avoid known risk factors for poor outcome, specifically the use of unwashed blood products.
Details
- Title: Subtitle
- Renal Transplantation After Streptococcus pneumoniae-Associated Hemolytic Uremic Syndrome
- Creators
- Damian J KrysanJoseph T Flynn
- Resource Type
- Journal article
- Publication Details
- American journal of kidney diseases, Vol.37(2), pp.e15.1-e15.8
- Publisher
- Elsevier Inc
- DOI
- 10.1053/ajkd.2001.21359
- PMID
- 11157401
- ISSN
- 0272-6386
- eISSN
- 1523-6838
- Language
- English
- Date published
- 02/2001
- Academic Unit
- Microbiology and Immunology; Stead Family Department of Pediatrics; Infectious Disease (Pediatrics)
- Record Identifier
- 9984093347002771
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