Repeat penetrating keratoplasty: indications, graft survival, and visual outcome

H Al-Mezaine; M D Wagoner; King Khaled Eye Specialist Hospital Cornea Transplant Study Group

doi:10.1136/bjo.2005.079624

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Repeat penetrating keratoplasty: indications, graft survival, and visual outcome

Journal article

Open access

Peer reviewed

Repeat penetrating keratoplasty: indications, graft survival, and visual outcome

H Al-Mezaine, M D Wagoner and King Khaled Eye Specialist Hospital Cornea Transplant Study Group

British journal of ophthalmology, Vol.90(3), pp.324-327

03/2006

DOI: 10.1136/bjo.2005.079624

PMCID: PMC1856933

PMID: 16488955

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https://doi.org/10.1136/bjo.2005.079624View

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Abstract

To determine graft survival and visual outcome after repeat penetrating keratoplasty (PKP). Retrospective review of the medical records patients who underwent repeat PKP at the King Khaled Eye Specialist Hospital (KKESH) between 1 January 1991 and 31 December 2002. 243 repeat PKP performed in 210 eyes of 208 patients, who had also had initial PKP at KKESH, were included in the study. The mean follow up was 43 months (range 1-170). At the most recent examination, 114 (54.3%) grafts were clear. The overall survival rate was 98% at 1 year, 83% at 2 years, and 49% at 5 years. The best graft survival was in eyes with an original diagnosis of keratoconus (93.8%) and the worst was in eyes with Fuchs' dystrophy (23.1%). Overall, 29.6% of eyes achieved a final visual acuity greater than 20/200, while only 4.8% were 20/40 or better. The best visual prognosis was in eyes with an original diagnosis of stromal dystrophy and keratoconus. Although the prognosis for repeat PKP is poorer than that of initial PKP, reasonable outcomes can be obtained with repeat PKP with careful case selection.

Reoperation

Prognosis

Humans

Middle Aged

Risk Factors

Graft Survival

Treatment Outcome

Visual Acuity

Corneal Diseases - surgery

Corneal Diseases - physiopathology

Adolescent

Keratoplasty, Penetrating

Aged, 80 and over

Adult

Aged

Retrospective Studies

Details

Title: Subtitle: Repeat penetrating keratoplasty: indications, graft survival, and visual outcome
Creators: H Al-Mezaine - King Khaled Eye Specialist Hospital, PO Box 7191, Riyadh 11462, Kingdom of Saudi Arabia. michaelwagoner625@yahoo.com
M D Wagoner
King Khaled Eye Specialist Hospital Cornea Transplant Study Group
Resource Type: Journal article
Publication Details: British journal of ophthalmology, Vol.90(3), pp.324-327
Publisher: England
DOI: 10.1136/bjo.2005.079624
PMID: 16488955
PMCID: PMC1856933
ISSN: 0007-1161
eISSN: 1468-2079
Language: English
Date published: 03/2006
Academic Unit: Ophthalmology and Visual Sciences
Record Identifier: 9983979906602771

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