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Replication Study Supports Evidence for Linkage to 9p24 in Obsessive-Compulsive Disorder
Journal article   Open access   Peer reviewed

Replication Study Supports Evidence for Linkage to 9p24 in Obsessive-Compulsive Disorder

Virginia L Willour, Yin Yao  Shugart, Jack Samuels, Marco Grados, Bernadette Cullen, O Joseph Bienvenu III, Ying Wang, Kung-Yee Liang, David Valle, Rudolf Hoehn-Saric, …
American journal of human genetics, Vol.75(3), pp.508-513
09/2004
DOI: 10.1086/423899
PMCID: PMC1182030
PMID: 15272418
url
https://doi.org/10.1086/423899View
Published (Version of record) Open Access

Abstract

Obsessive-compulsive disorder (OCD) is a severe psychiatric illness that is characterized by intrusive and senseless thoughts and impulses (obsessions) and by repetitive behaviors (compulsions). Family, twin, and segregation studies support the presence of both genetic and environmental susceptibility factors, and the only published genome scan for OCD identified a candidate region on 9p24 at marker D9S288 that met criteria for suggestive significance (Hanna et al.
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