Representation of interaural time delay in the human auditory midbrain

Sarah K Thompson; Katharina von Kriegstein; Adenike Deane-Pratt; Torsten Marquardt; Ralf Deichmann; Timothy D Griffiths; David McAlpine

doi:10.1038/nn1755

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Representation of interaural time delay in the human auditory midbrain

Journal article

Peer reviewed

Representation of interaural time delay in the human auditory midbrain

Sarah K Thompson, Katharina von Kriegstein, Adenike Deane-Pratt, Torsten Marquardt, Ralf Deichmann, Timothy D Griffiths and David McAlpine

Nature neuroscience, Vol.9(9), pp.1096-1098

09/01/2006

DOI: 10.1038/nn1755

PMID: 16921369

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Abstract

Interaural time difference (ITD) is a critical cue to sound-source localization. Traditional models assume that sounds leading at one ear, and perceived on that side, are processed in the opposite midbrain. Using functional magnetic resonance imaging we demonstrate that as the ITDs of sounds increase, midbrain activity can switch sides, even though perceived location remains on the same side. The data require a new model for human ITD processing.

Acoustic Stimulation

Auditory Pathways - physiology

Auditory Perception - physiology

Cues

Ear - physiology

Evoked Potentials, Auditory - physiology

Humans

Magnetic Resonance Imaging - methods

Mesencephalon - physiology

Models, Neurological

Sound Localization - physiology

Time Factors

Details

Title: Subtitle: Representation of interaural time delay in the human auditory midbrain
Creators: Sarah K Thompson - Department of Physiology and UCL Ear Institute, University College London, 332 Gray's Inn Road, London WC1X 8EE, UK
Katharina von Kriegstein - Wellcome Centre for Human Neuroimaging
Adenike Deane-Pratt - University College London
Torsten Marquardt - University College London
Ralf Deichmann - Wellcome Centre for Human Neuroimaging
Timothy D Griffiths - Wellcome Centre for Human Neuroimaging
David McAlpine - University College London
Resource Type: Journal article
Publication Details: Nature neuroscience, Vol.9(9), pp.1096-1098
DOI: 10.1038/nn1755
PMID: 16921369
ISSN: 1097-6256
eISSN: 1546-1726
Grant note: G0300417 / Medical Research Council Wellcome Trust
Language: English
Date published: 09/01/2006
Academic Unit: Psychological and Brain Sciences
Record Identifier: 9984627231502771

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