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Reproducibility of subregional trabecular bone micro-architectural measures derived from 7-Tesla magnetic resonance images
Journal article   Open access   Peer reviewed

Reproducibility of subregional trabecular bone micro-architectural measures derived from 7-Tesla magnetic resonance images

Gregory Chang, Ligong Wang, Guoyuan Liang, James S Babb, Punam K Saha and Ravinder R Regatte
Magma (New York, N.Y.), Vol.24(3), pp.121-125
06/2011
DOI: 10.1007/s10334-010-0243-6
PMCID: PMC3710719
PMID: 21221706
url
https://www.ncbi.nlm.nih.gov/pmc/articles/3710719View
Open Access

Abstract

High-resolution magnetic resonance imaging (MRI) of trabecular bone combined with quantitative image analysis represents a powerful technique to gain insight into trabecular bone micro-architectural derangements in osteoporosis and osteoarthritis. The increased signal-to-noise ratio of ultra high-field MR (≥7 Tesla) permits images to be obtained with higher resolution and/or decreased scan time compared to scanning at 1.5/3T. In this small feasibility study, we show high measurement precision for subregional trabecular bone micro-architectural analysis performed on 7T knee MR images. The results provide further support for the use of trabecular bone measures as biomarkers in clinical studies of bone disorders.
Ultra high field Knee Trabecular bone MRI Micro-architecture 7 Tesla

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