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Research Methods in Healthcare Epidemiology and Antimicrobial Stewardship-Quasi-Experimental Designs
Journal article   Peer reviewed

Research Methods in Healthcare Epidemiology and Antimicrobial Stewardship-Quasi-Experimental Designs

Marin L Schweizer, Barbara I Braun and Aaron M Milstone
Infection control and hospital epidemiology, Vol.37(10), pp.1135-1140
10/2016
DOI: 10.1017/ice.2016.117
PMCID: PMC5036994
PMID: 27267457
url
http://doi.org/10.1017/ice.2016.117View
Open Access

Abstract

Quasi-experimental studies evaluate the association between an intervention and an outcome using experiments in which the intervention is not randomly assigned. Quasi-experimental studies are often used to evaluate rapid responses to outbreaks or other patient safety problems requiring prompt, nonrandomized interventions. Quasi-experimental studies can be categorized into 3 major types: interrupted time-series designs, designs with control groups, and designs without control groups. This methods paper highlights key considerations for quasi-experimental studies in healthcare epidemiology and antimicrobial stewardship, including study design and analytic approaches to avoid selection bias and other common pitfalls of quasi-experimental studies. Infect Control Hosp Epidemiol 2016;1-6.
 Data Interpretation, Statistical Epidemiologic Studies Antimicrobial Stewardship Interrupted Time Series Analysis Epidemiologic Methods Bias Humans Control Groups Research Design

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