Resistance to activated protein C (APC) in Indian patients of thrombophilia

H P Pati; A Srivastava; S Dayal

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Resistance to activated protein C (APC) in Indian patients of thrombophilia

Journal article

Peer reviewed

Resistance to activated protein C (APC) in Indian patients of thrombophilia

H P Pati, A Srivastava and S Dayal

Indian journal of medical research (New Delhi, India : 1994), Vol.104, pp.213-215

09/1996

PMID: 8898480

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Abstract

In a pilot study, 28 consecutive patients with thrombosis and 23 age and sex matched healthy normal controls were investigated with normalised APC sensitivity ratio (n-APC-SR) to know the defect exists and if so its prevalence in India. Six of the 28 (21.4%) thrombotic patients had n-APC-SR of < 0.76 (range 0.55 to 0.74) as compared to the normal control value (0.97 +/- 0.105). Our study shows APC resistance defect in a significant proportion (21.4%) of Indian patients with thrombotic disorders.

India

Disease Susceptibility

Humans

Middle Aged

Male

Case-Control Studies

Adolescent

Adult

Female

Enzyme Activation

Protein C - metabolism

Thrombosis - blood

Child

Details

Title: Subtitle: Resistance to activated protein C (APC) in Indian patients of thrombophilia
Creators: H P Pati - Department of Haematology, All India Institute of Medical Sciences, New Delhi
A Srivastava
S Dayal
Resource Type: Journal article
Publication Details: Indian journal of medical research (New Delhi, India : 1994), Vol.104, pp.213-215
Publisher: India
PMID: 8898480
ISSN: 0971-5916
Language: English
Date published: 09/1996
Academic Unit: Hematology, Oncology, and Blood & Marrow Transplantation; Iowa Neuroscience Institute; Fraternal Order of Eagles Diabetes Research Center; Internal Medicine
Record Identifier: 9984065496802771

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