Journal article
Respiratory dendritic cells: maturation and migration following pulmonary influenza virus infection
International Congress series, Vol.1263(C), pp.149-152
2004
DOI: 10.1016/j.ics.2004.02.027
Abstract
Following uptake of either innocuous or pathogenic antigens, dendritic cells (DC) are thought to mature and then migrate to the regional lymph nodes, where they present this antigen to naı̈ve T and B cells resulting in peripheral tolerance or the induction of the adaptive immune response, respectively. Respiratory dendritic cells (rDC) reside throughout the respiratory tract where they are thought to participate in immune surveillance by sampling the pulmonary environment, yet surprisingly little is known about their maturation and migration. Recently, using a novel in situ CFSE labeling technique, we have explored rDC maturation and migration to the regional lymph nodes both in the steady state and following intranasal (i.n.) influenza virus infection.
Details
- Title: Subtitle
- Respiratory dendritic cells: maturation and migration following pulmonary influenza virus infection
- Creators
- Kevin L Legge - University of VirginiaThomas J Braciale - University of Virginia
- Resource Type
- Journal article
- Publication Details
- International Congress series, Vol.1263(C), pp.149-152
- Publisher
- Elsevier B.V
- DOI
- 10.1016/j.ics.2004.02.027
- ISSN
- 0531-5131
- eISSN
- 1873-6157
- Language
- English
- Date published
- 2004
- Academic Unit
- Microbiology and Immunology; Pathology
- Record Identifier
- 9984186484502771
Metrics
3 Record Views