Journal article
Respiratory dendritic cells: mediators of tolerance and immunity
Immunologic research, Vol.39(1-3), pp.128-145
2007
DOI: 10.1007/s12026-007-0077-0
PMID: 17917061
Abstract
The respiratory tract is under constant bombardment from both innocuous and pathogenic material. The decision of how to respond to these challenges is mediated by a specialized set of antigen presenting cells within the lungs called dendritic cells (DC). Proper respiratory homeostasis requires that these respiratory DC (rDC) utilize both the local lung inflammatory environment as well as recognition of pathogen-specific patterns to determine whether to maintain homeostasis by either driving tolerance or immunity to the inhaled material. This review will focus on rDC and highlight how rDC regulate tolerance and immunity.
Details
- Title: Subtitle
- Respiratory dendritic cells: mediators of tolerance and immunity
- Creators
- Ryan A Langlois - Department of Pathology, Immunology Graduate Program, University of Iowa, Iowa City, IA 52242, USAKevin L Legge
- Resource Type
- Journal article
- Publication Details
- Immunologic research, Vol.39(1-3), pp.128-145
- Publisher
- United States
- DOI
- 10.1007/s12026-007-0077-0
- PMID
- 17917061
- ISSN
- 0257-277X
- eISSN
- 1559-0755
- Language
- English
- Date published
- 2007
- Academic Unit
- Microbiology and Immunology; Pathology
- Record Identifier
- 9984047750202771
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