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Respiratory symptoms as an initial presentation of choriocarcinoma
Journal article   Peer reviewed

Respiratory symptoms as an initial presentation of choriocarcinoma

Ramandeep Singh, Paramdeep Singh, Rupinderjeet Kaur, Rubal Rai and Simmi Aggarwal
Clinical cancer investigation journal, Vol.4(4), pp.555-557
07/01/2015
DOI: 10.4103/2278-0513.157941

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Abstract

Chronic dyspnea, chest pain, cough, and hemoptysis for more than 2 weeks often indicate a diagnosis of infective etiology of the respiratory tract in a tropical country. However, in a young reproductive female, these complaints with an episode of hemoptysis may rarely be the presenting symptomatology of pulmonary metastasis of choriocarcinoma. A young female of reproductive age group presented with hemoptysis, cough, and breathlessness. Chest X-ray revealed bilateral lower lobe opacities. Fine-needle aspiration cytology of the lung lesions depicted choriocarcinoma metastasis. Ultrasonography and magnetic resonance imaging revealed endomyometrial mass lesion suggestive of invasive gestational trophoblastic disease. beta hCG levels were high. Dilatation and curettage and histopathological analysis of the mass confirmed the diagnosis of choriocarcinoma. This young female who presented with respiratory complaints was finally diagnosed to be a case of choriocarcinoma with lung metastasis. Therefore, choriocarcinoma metastasis must be considered as a differential diagnosis in a female of childbearing age presenting with respiratory complaints and hemoptysis.
 Life Sciences & Biomedicine Oncology Science & Technology

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