Journal article
Response to Comment on “Remeasuring the Double Helix”
Science (American Association for the Advancement of Science), Vol.325(5940), pp.538-538
07/31/2009
DOI: 10.1126/science.1168876
Abstract
We measured the mean and variance of end-to-end length in short DNA fragments in solution and reported evidence of DNA stretching that is cooperative over more than two turns of the double helix. Becker and Everaers suggest that the structural fluctuations we observed arise from bending motions of the DNA, rather than stretching. We present three experimental tests of this bending-based explanation.
Details
- Title: Subtitle
- Response to Comment on “Remeasuring the Double Helix”
- Creators
- Rebecca S Mathew-Fenn - Biophysics Program, Stanford University, Stanford, CA 94305, USA., Department of Biochemistry, Stanford University, Stanford, CA 94305, USARhiju Das - Biophysics Program, Stanford University, Stanford, CA 94305, USA., Department of Biochemistry, Stanford University, Stanford, CA 94305, USATimothy D Fenn - Department of Chemistry and Structural Biology, Stanford University, Stanford, CA 94305, USAMichael Schneiders - Department of Chemistry and Structural Biology, Stanford University, Stanford, CA 94305, USAPehr A. B Harbury - Biophysics Program, Stanford University, Stanford, CA 94305, USA., Department of Biochemistry, Stanford University, Stanford, CA 94305, USA
- Resource Type
- Journal article
- Publication Details
- Science (American Association for the Advancement of Science), Vol.325(5940), pp.538-538
- DOI
- 10.1126/science.1168876
- ISSN
- 0036-8075
- eISSN
- 1095-9203
- Language
- English
- Date published
- 07/31/2009
- Academic Unit
- Roy J. Carver Department of Biomedical Engineering; Biochemistry and Molecular Biology; Chemical and Biochemical Engineering
- Record Identifier
- 9984024510502771
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