Journal article
Results of radical perineal prostatectomy with adjuvant brachytherapy
Radiology, Vol.184(2), pp.333-339
1992
DOI: 10.1148/radiology.184.2.1620824
PMID: 1620824
Abstract
Retrospective analysis of outcome in 137 patients who underwent radical perineal prostatectomy and bilateral injection of gold-198 implants into the periprostatic tissues and/or neurovascular pedicles as treatment for prostatic adenocarcinoma was performed. Patients had undergone treatment between 1975 and 1985. Local recurrence developed in 22 patients (16.1%) and distant metastases developed in 33 (24.1%). Clinical and surgical staging of disease and Gleason grading of pathologic specimens were performed retrospectively. Kaplan-Meier local recurrence, freedom from relapse (FFR), and survival rates decreased with increasing stage and pathologic grade. With clinical staging, these rates were not statistically different from previous rates achieved with external beam radiation therapy, and with pathologic staging, they were not statistically different from previous rates achieved with prostatectomy. The authors conclude that (a) 5-year follow-up is inadequate to determine local control rates after prostatectomy; (b) use of implants did not improve local control, FFR, or survival rates of 10 years; and (c) method of staging probably has more effect on local control, FFR, and survival rates than does treatment modality.
Details
- Title: Subtitle
- Results of radical perineal prostatectomy with adjuvant brachytherapy
- Creators
- J. F DOORNBOS - Univ. Iowa coll. medicine, dep. radiology, div. radiation oncology, Iowa City IA 52242-1009, United StatesD. H HUSSEY - Univ. Iowa coll. medicine, dep. radiology, div. radiation oncology, Iowa City IA 52242-1009, United StatesR. A ROBINSON - Univ. Iowa coll. medicine, dep. radiology, div. radiation oncology, Iowa City IA 52242-1009, United StatesB.-C WEN - Univ. Iowa coll. medicine, dep. radiology, div. radiation oncology, Iowa City IA 52242-1009, United StatesA. P VIGLIOTTI - Univ. Iowa coll. medicine, dep. radiology, div. radiation oncology, Iowa City IA 52242-1009, United States
- Resource Type
- Journal article
- Publication Details
- Radiology, Vol.184(2), pp.333-339
- Publisher
- Radiological Society of North America; Oak Brook, IL
- DOI
- 10.1148/radiology.184.2.1620824
- PMID
- 1620824
- ISSN
- 0033-8419
- eISSN
- 1527-1315
- Language
- English
- Date published
- 1992
- Academic Unit
- Oral Pathology, Radiology and Medicine; Pathology
- Record Identifier
- 9984047684002771
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