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Retrospective evaluation of intersubject brain registration
Journal article   Peer reviewed

Retrospective evaluation of intersubject brain registration

Pierre Hellier, Christian Barillot, Isabelle Corouge, Bernard Gibaud, G Le Goualher, D. Louis Collins, Allan Evans, Grégoire Malandain, Nicholas Ayache, G. E Christensen, …
IEEE transactions on medical imaging, Vol.22(9), pp.1120-1130
09/08/2003
DOI: 10.1109/TMI.2003.816961
PMID: 12956267

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Abstract

Although numerous methods to register brains of different individuals have been proposed, no work has been done, as far as we know, to evaluate and objectively compare the performances of different nonrigid (or elastic) registration methods on the same database of subjects. In this paper, we propose an evaluation framework, based on global and local measures of the relevance of the registration. We have chosen to focus more particularly on the matching of cortical areas, since intersubject registration methods are dedicated to anatomical and functional normalization, and also because other groups [7] have shown the relevance of such registration methods for deep brain structures. Experiments were conducted using 6 methods on a database of 18 subjects. The global measures used show that the quality of the registration is directly related to the transformation's degrees of freedom. More surprisingly, local measures based on the matching of cortical sulci did not show significant differences between rigid and non rigid methods.
Computer Science Information Retrieval

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