Reusable acoustic tweezers for disposable devices

Feng Guo; Yuliang Xie; Sixing Li; James Lata; Liqiang Ren; Zhangming Mao; Baiyang Ren; Mengxi Wu; Adem Ozcelik; Tony Jun Huang

doi:10.1039/C5LC01049G

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Reusable acoustic tweezers for disposable devices

Journal article

Peer reviewed

Reusable acoustic tweezers for disposable devices

Feng Guo, Yuliang Xie, Sixing Li, James Lata, Liqiang Ren, Zhangming Mao, Baiyang Ren, Mengxi Wu, Adem Ozcelik and Tony Jun Huang

Lab on a chip, Vol.15(24), pp.4517-4523

2015

DOI: 10.1039/C5LC01049G

PMCID: PMC4683015

PMID: 26507411

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https://www.ncbi.nlm.nih.gov/pmc/articles/4683015View

Open Access

Abstract

We demonstrate acoustic tweezers used for disposable devices. Rather than forming an acoustic resonance, we locally transmitted standing surface acoustic waves into a removable, independent polydimethylsiloxane (PDMS)-glass hybridized microfluidic superstrate device for micromanipulation. By configuring and regulating the displacement nodes on a piezoelectric substrate, cells and particles were effectively patterned and transported into said superstrate, accordingly. With the label-free and contactless nature of acoustic waves, the presented technology could offer a simple, accurate, low-cost, biocompatible, and disposable method for applications in the fields of point-of-care diagnostics and fundamental biomedical studies.

Details

Title: Subtitle: Reusable acoustic tweezers for disposable devices
Creators: Feng Guo - Pennsylvania State University
Yuliang Xie - Pennsylvania State University
Sixing Li - Pennsylvania State University
James Lata - Pennsylvania State University
Liqiang Ren - Pennsylvania State University
Zhangming Mao - Pennsylvania State University
Baiyang Ren - Pennsylvania State University
Mengxi Wu - Pennsylvania State University
Adem Ozcelik - Pennsylvania State University
Tony Jun Huang - Pennsylvania State University
Resource Type: Journal article
Publication Details: Lab on a chip, Vol.15(24), pp.4517-4523
DOI: 10.1039/C5LC01049G
PMID: 26507411
PMCID: PMC4683015
NLM abbreviation: Lab Chip
ISSN: 1473-0197
eISSN: 1473-0189
Grant note: DOI: 10.13039/100000009, name: Foundation for the National Institutes of Health, award: 1 R01 GM112048-01A1, 1R33EB019785-01; DOI: 10.13039/100000084, name: Directorate for Engineering, award: IDBR-1455658, IIP-1534645
Language: English
Date published: 2015
Academic Unit: Roy J. Carver Department of Biomedical Engineering
Record Identifier: 9984197005002771

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