Review of Two Popular Eating Plans within the Multiple Sclerosis Community: Low Saturated Fat and Modified Paleolithic

Terry L Wahls; Catherine A Chenard; Linda G Snetselaar

doi:10.3390/nu11020352

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Review of Two Popular Eating Plans within the Multiple Sclerosis Community: Low Saturated Fat and Modified Paleolithic

Journal article

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Review of Two Popular Eating Plans within the Multiple Sclerosis Community: Low Saturated Fat and Modified Paleolithic

Terry L Wahls, Catherine A Chenard and Linda G Snetselaar

Nutrients, Vol.11(2), p.352

2019

DOI: 10.3390/nu11020352

PMCID: PMC6412750

PMID: 30736445

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Abstract

The precise etiology of multiple sclerosis (MS) is unknown but epidemiologic evidence suggests this immune-mediated, neurodegenerative condition is the result of a complex interaction between genes and lifetime environmental exposures. Diet choices are modifiable environmental factors that may influence MS disease activity. Two diets promoted for MS, low saturated fat Swank and modified Paleolithic Wahls Elimination (WahlsElim), are currently being investigated for their effect on MS-related fatigue and quality of life (NCT02914964). Dr. Swank theorized restriction of saturated fat would reduce vascular dysfunction in the central nervous system (CNS). Dr. Wahls initially theorized that detailed guidance to increase intake of specific foodstuffs would facilitate increased intake of nutrients key to neuronal health (Wahls™ diet). Dr. Wahls further theorized restriction of lectins would reduce intestinal permeability and CNS inflammation (WahlsElim version). The purpose of this paper is to review the published research of the low saturated fat (Swank) and the modified Paleolithic (Wahls™) diets and the rationale for the structure of the Swank diet and low lectin version of the Wahls™ diet (WahlsElim) being investigated in the clinical trial.

low saturated fat diet

Wahls diet

multiple sclerosis

Wahls Elimination diet

modified Paleolithic diet

Review

Paleolithic diet

Swank diet

Details

Title: Subtitle: Review of Two Popular Eating Plans within the Multiple Sclerosis Community: Low Saturated Fat and Modified Paleolithic
Creators: Terry L Wahls - Department of Epidemiology, College of Public Health, University of Iowa, Iowa City, IA 52242, USA
Catherine A Chenard - Department of Epidemiology, College of Public Health, University of Iowa, Iowa City, IA 52242, USA
Linda G Snetselaar - Department of Epidemiology, College of Public Health, University of Iowa, Iowa City, IA 52242, USA
Resource Type: Journal article
Publication Details: Nutrients, Vol.11(2), p.352
DOI: 10.3390/nu11020352
PMID: 30736445
PMCID: PMC6412750
NLM abbreviation: Nutrients
ISSN: 2072-6643
eISSN: 2072-6643
Publisher: MDPI
Language: English
Date published: 2019
Academic Unit: Neurology; Epidemiology; General Internal Medicine; Internal Medicine
Record Identifier: 9983996192702771

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