Journal article
Rhinoscleroma with Pharyngolaryngeal Involvement Caused by Klebsiella ozaenae
Case reports in infectious diseases, Vol.2016, pp.6536275-6536275
2016
DOI: 10.1155/2016/6536275
PMCID: PMC4880720
PMID: 27293924
Abstract
Rhinoscleroma is a chronic, slowly progressive granulomatous bacterial infection that is endemic to the tropical world, namely, Central America and Africa. It is occasionally seen in the United States of America (USA). It predominately affects the nasal mucosa but can also involve the rest of the upper respiratory tract. The well-known causative agent for rhinoscleroma is the bacterium
Klebsiella rhinoscleromatis
, a subspecies of
Klebsiella pneumoniae
. However,
Klebsiella ozaenae
can also, albeit very rarely, cause rhinoscleroma. The diagnosis is confirmed by histopathology examination that shows the characteristic Mikulicz cells, considered pathognomonic for this infection. We report a patient with histologically proven rhinoscleroma with pharyngolaryngeal involvement in whom cultures yielded
Klebsiella ozaenae
. To the best of our knowledge, only two cases of rhinoscleroma due to
Klebsiella ozaenae
have been reported in the literature to date. Our case illustrates the importance of recognizing this infection in a nonendemic setting such as the USA. A lack of awareness and a delay in the diagnosis of this disease can lead to complications including upper airway obstruction, physical deformity, and, rarely, sepsis. In addition, it must be remembered that the treatment of rhinoscleroma is challenging and requires a prolonged course of antibiotics to achieve a definite cure and avoid relapses.
Details
- Title: Subtitle
- Rhinoscleroma with Pharyngolaryngeal Involvement Caused by Klebsiella ozaenae
- Creators
- J Gonzales Zamora - Division of Infectious Diseases, Augusta University, Augusta, GA 30912, USAA. R Murali - Department of Gastroenterology, University of Iowa Hospital and Clinics, Iowa City, IA 52242, USA
- Resource Type
- Journal article
- Publication Details
- Case reports in infectious diseases, Vol.2016, pp.6536275-6536275
- DOI
- 10.1155/2016/6536275
- PMID
- 27293924
- PMCID
- PMC4880720
- NLM abbreviation
- Case Rep Infect Dis
- ISSN
- 2090-6625
- eISSN
- 2090-6633
- Publisher
- Hindawi Publishing Corporation
- Language
- English
- Date published
- 2016
- Academic Unit
- Gastroenterology and Hepatology; Internal Medicine
- Record Identifier
- 9984094310802771
Metrics
17 Record Views