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Right Ventricle Myxoma Masquerading as a Thrombus in a Pediatric Patient
Journal article   Open access   Peer reviewed

Right Ventricle Myxoma Masquerading as a Thrombus in a Pediatric Patient

Nikhila Rao, Nilesh Rao, George Alfieris, Christopher Prendergast and Rajiv Devanagondi
JACC. Case reports, Vol.30(14), 103620
06/11/2025
DOI: 10.1016/j.jaccas.2025.103620
PMCID: PMC12237734
PMID: 40514121
url
https://doi.org/10.1016/j.jaccas.2025.103620View
Published (Version of record) Open Access

Abstract

Primary cardiac tumors are uncommon in pediatric patients, particularly myxomas. Right ventricle (RV) myxomas can lead to life-threatening sequelae such as pulmonary embolism. A teenage patient presented with chest pain, was initially diagnosed with pulmonary emboli, and ultimately diagnosed with RV myxoma after transcatheter echocardiographic-guided biopsy of the intracardiac mass. The myxoma was surgically resected, and the patient fully recovered. Intracardiac myxomas are unusual in pediatric patients, particularly myxomas arising from the RV. Prior reports of RV myxoma associated with distal pulmonary emboli in children have been fatal or associated with Carney complex. In unusual cases, transcatheter biopsy can confirm the diagnosis. A high degree of suspicion is required to diagnose pediatric myxoma, particularly when it resembles other intracardiac masses, such as thrombus. Additionally, multimodality imaging and biopsy may help to establish a definitive diagnosis before surgical resection.
 Pediatric Surgery cancer thrombus pulmonary circulation imaging anticoagulation

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